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OLFML1 olfactomedin like 1 [ Homo sapiens (human) ]

Gene ID: 283298, updated on 12-Aug-2022

Summary

Official Symbol
OLFML1provided by HGNC
Official Full Name
olfactomedin like 1provided by HGNC
Primary source
HGNC:HGNC:24473
See related
Ensembl:ENSG00000183801 AllianceGenome:HGNC:24473
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
UNQ564; MVAL564
Summary
Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary (RPKM 18.5), gall bladder (RPKM 12.2) and 22 other tissues See more
Orthologs
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Genomic context

See OLFML1 in Genome Data Viewer
Location:
11p15.4
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (7485506..7511377)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (7543862..7569737)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (7506737..7532608)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene microRNA 302e Neighboring gene synaptotagmin 9 Neighboring gene Sharpr-MPRA regulatory region 13298 Neighboring gene SYT9 antisense RNA 1 Neighboring gene leucine-rich repeat extensin-like protein 5 Neighboring gene PPFIA binding protein 2 Neighboring gene uncharacterized LOC105376535 Neighboring gene cytochrome b5 reductase 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
olfactomedin-like protein 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001370498.1NP_001357427.1  olfactomedin-like protein 1 isoform a precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2), as well as variant 1, encodes the longest isoform (a).
    Source sequence(s)
    AC107884
    UniProtKB/Swiss-Prot
    Q569G4
    Related
    ENSP00000433455.1, ENST00000530135.5
    Conserved Domains (1) summary
    pfam02191
    Location:145393
    OLF; Olfactomedin-like domain
  2. NM_001370499.1NP_001357428.1  olfactomedin-like protein 1 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC107884, AK297778
    UniProtKB/TrEMBL
    B4DN61
    Conserved Domains (1) summary
    pfam02191
    Location:9257
    OLF; Olfactomedin-like domain
  3. NM_001370500.1NP_001357429.1  olfactomedin-like protein 1 isoform c precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4), as well as variant 5, encodes isoform c.
    Source sequence(s)
    AC107884
  4. NM_001370501.1NP_001357430.1  olfactomedin-like protein 1 isoform c precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5), as well as variant 4, encodes isoform c.
    Source sequence(s)
    AC107884
  5. NM_198474.4NP_940876.2  olfactomedin-like protein 1 isoform a precursor

    See identical proteins and their annotated locations for NP_940876.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AC107884, AK298137, BX647908, DB257515, DC397336
    Consensus CDS
    CCDS7779.1
    UniProtKB/Swiss-Prot
    Q569G4, Q6UWY5
    UniProtKB/TrEMBL
    Q5HYE3
    Related
    ENSP00000332511.3, ENST00000329293.4
    Conserved Domains (1) summary
    pfam02191
    Location:145393
    OLF; Olfactomedin-like domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    7485506..7511377
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    7543862..7569737
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)