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OR9G4 olfactory receptor family 9 subfamily G member 4 [ Homo sapiens (human) ]

Gene ID: 283189, updated on 25-Nov-2021

Summary

Official Symbol
OR9G4provided by HGNC
Official Full Name
olfactory receptor family 9 subfamily G member 4provided by HGNC
Primary source
HGNC:HGNC:15322
See related
Ensembl:ENSG00000172457
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR11-216
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR9G4 in Genome Data Viewer
Location:
11q12.1
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (56741223..56748697, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (56510304..56511287, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 9 subfamily G member 1 Neighboring gene olfactory receptor family 9 subfamily G member 3 pseudogene Neighboring gene microRNA 6128 Neighboring gene olfactory receptor family 9 subfamily G member 2 pseudogene Neighboring gene olfactory receptor family 5 subfamily G member 1 pseudogene

Genomic regions, transcripts, and products

Phenotypes

Associated conditions

Description Tests
Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.
GeneReviews: Not available

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables odorant binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in detection of chemical stimulus involved in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
 
involved_in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 9G4
Names
olfactory receptor OR11-216

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005284.2NP_001005284.2  olfactory receptor 9G4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AP001803
    Consensus CDS
    CCDS31537.1
    Related
    ENSP00000493182.1, ENST00000641668.1
    Conserved Domains (1) summary
    cd15418
    Location:24304
    7tmA_OR9G-like; olfactory receptor subfamily 9G and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
  2. NM_001390832.1NP_001377761.1  olfactory receptor 9G4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AP001803
    Related
    ENSP00000493212.1, ENST00000641581.1
    Conserved Domains (1) summary
    cd15418
    Location:24304
    7tmA_OR9G-like; olfactory receptor subfamily 9G and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    56741223..56748697 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_1

Genomic

  1. NW_003871074.1 Reference GRCh38.p13 ALT_REF_LOCI_1

    Range
    59065..66539 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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