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JAKMIP3 Janus kinase and microtubule interacting protein 3 [ Homo sapiens (human) ]

Gene ID: 282973, updated on 23-Nov-2021

Summary

Official Symbol
JAKMIP3provided by HGNC
Official Full Name
Janus kinase and microtubule interacting protein 3provided by HGNC
Primary source
HGNC:HGNC:23523
See related
Ensembl:ENSG00000188385 MIM:611198
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NECC2; Jamip3; C10orf14; C10orf39; bA140A10.5
Expression
Biased expression in brain (RPKM 2.2), prostate (RPKM 1.0) and 11 other tissues See more
Orthologs
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Try the new Transcript table

Genomic context

See JAKMIP3 in Genome Data Viewer
Location:
10q26.3
Exon count:
31
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (132036068..132184858)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (133879450..133998362)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L19-like Neighboring gene protein phosphatase 2 regulatory subunit Bdelta Neighboring gene BCL2 interacting protein 3 Neighboring gene JAKMIP3 antisense RNA 1 Neighboring gene dihydropyrimidinase like 4 Neighboring gene serine/threonine kinase 32C Neighboring gene Sharpr-MPRA regulatory region 5064

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

Associated conditions

Description Tests
Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ37857, FLJ41432

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables kinase binding IEA
Inferred from Electronic Annotation
more info
 
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
janus kinase and microtubule-interacting protein 3
Names
neuroendocrine long coiled-coil 2
neuroendocrine long coiled-coil protein 2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105521.4NP_001098991.1  janus kinase and microtubule-interacting protein 3 isoform e

    See identical proteins and their annotated locations for NP_001098991.1

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Consensus CDS
    CCDS44494.1
    UniProtKB/Swiss-Prot
    Q5VZ66
    Related
    ENSP00000298622.4, ENST00000298622.9
    Conserved Domains (2) summary
    TIGR02168
    Location:27818
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:430625
    JAKMIP_CC3; JAKMIP CC3 domain
  2. NM_001323086.2NP_001310015.1  janus kinase and microtubule-interacting protein 3 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Related
    ENSP00000499222.1, ENST00000666210.1
    Conserved Domains (2) summary
    TIGR02168
    Location:27831
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:430625
    JAKMIP_CC3; JAKMIP CC3 domain
  3. NM_001323087.2NP_001310016.1  janus kinase and microtubule-interacting protein 3 isoform b

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Related
    ENSP00000499291.1, ENST00000657785.1
    Conserved Domains (2) summary
    TIGR02168
    Location:27820
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:430625
    JAKMIP_CC3; JAKMIP CC3 domain
  4. NM_001323088.2NP_001310017.1  janus kinase and microtubule-interacting protein 3 isoform c

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
  5. NM_001323089.2NP_001310018.1  janus kinase and microtubule-interacting protein 3 isoform d

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Related
    ENSP00000499560.1, ENST00000657318.1
  6. NM_001323090.2NP_001310019.1  janus kinase and microtubule-interacting protein 3 isoform e

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) and variant 5 both encode the same isoform (e).
    Source sequence(s)
    AL162274, AL512622
    Consensus CDS
    CCDS44494.1
    UniProtKB/Swiss-Prot
    Q5VZ66
    Conserved Domains (2) summary
    TIGR02168
    Location:27818
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:430625
    JAKMIP_CC3; JAKMIP CC3 domain
  7. NM_001392039.1NP_001378968.1  janus kinase and microtubule-interacting protein 3 isoform f

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Conserved Domains (2) summary
    TIGR02168
    Location:27835
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:428623
    JAKMIP_CC3; JAKMIP CC3 domain
  8. NM_001392040.1NP_001378969.1  janus kinase and microtubule-interacting protein 3 isoform g

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Conserved Domains (2) summary
    TIGR02169
    Location:45830
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    pfam16034
    Location:430625
    JAKMIP_CC3; JAKMIP CC3 domain
  9. NM_001392041.1NP_001378970.1  janus kinase and microtubule-interacting protein 3 isoform b

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Conserved Domains (2) summary
    TIGR02168
    Location:27820
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:430625
    JAKMIP_CC3; JAKMIP CC3 domain
  10. NM_001392042.1NP_001378971.1  janus kinase and microtubule-interacting protein 3 isoform b

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Related
    ENSP00000499416.1, ENST00000666974.1
    Conserved Domains (2) summary
    TIGR02168
    Location:27820
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:430625
    JAKMIP_CC3; JAKMIP CC3 domain
  11. NM_001392043.1NP_001378972.1  janus kinase and microtubule-interacting protein 3 isoform e

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Related
    ENSP00000499753.1, ENST00000668452.1
    Conserved Domains (2) summary
    TIGR02168
    Location:27818
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:430625
    JAKMIP_CC3; JAKMIP CC3 domain
  12. NM_001392044.1NP_001378973.1  janus kinase and microtubule-interacting protein 3 isoform e

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Conserved Domains (2) summary
    TIGR02168
    Location:27818
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:430625
    JAKMIP_CC3; JAKMIP CC3 domain
  13. NM_001392045.1NP_001378974.1  janus kinase and microtubule-interacting protein 3 isoform e

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Conserved Domains (2) summary
    TIGR02168
    Location:27818
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:430625
    JAKMIP_CC3; JAKMIP CC3 domain
  14. NM_001392046.1NP_001378975.1  janus kinase and microtubule-interacting protein 3 isoform e

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Conserved Domains (2) summary
    TIGR02168
    Location:27818
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:430625
    JAKMIP_CC3; JAKMIP CC3 domain
  15. NM_001392047.1NP_001378976.1  janus kinase and microtubule-interacting protein 3 isoform e

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Related
    ENSP00000499375.1, ENST00000664697.1
    Conserved Domains (2) summary
    TIGR02168
    Location:27818
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:430625
    JAKMIP_CC3; JAKMIP CC3 domain
  16. NM_001392048.1NP_001378977.1  janus kinase and microtubule-interacting protein 3 isoform h

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Conserved Domains (2) summary
    TIGR02168
    Location:27818
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:430623
    JAKMIP_CC3; JAKMIP CC3 domain
  17. NM_001392049.1NP_001378978.1  janus kinase and microtubule-interacting protein 3 isoform h

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Conserved Domains (2) summary
    TIGR02168
    Location:27818
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:430623
    JAKMIP_CC3; JAKMIP CC3 domain
  18. NM_001392050.1NP_001378979.1  janus kinase and microtubule-interacting protein 3 isoform i

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Conserved Domains (2) summary
    TIGR02168
    Location:27816
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:428621
    JAKMIP_CC3; JAKMIP CC3 domain
  19. NM_001392051.1NP_001378980.1  janus kinase and microtubule-interacting protein 3 isoform j

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Conserved Domains (2) summary
    TIGR02168
    Location:27815
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:427622
    JAKMIP_CC3; JAKMIP CC3 domain
  20. NM_001392052.1NP_001378981.1  janus kinase and microtubule-interacting protein 3 isoform k

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Related
    ENSP00000499285.1, ENST00000653512.1
    Conserved Domains (2) summary
    TIGR02168
    Location:27809
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:428623
    JAKMIP_CC3; JAKMIP CC3 domain
  21. NM_001392053.1NP_001378982.1  janus kinase and microtubule-interacting protein 3 isoform l

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Conserved Domains (2) summary
    TIGR02168
    Location:27765
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:358551
    JAKMIP_CC3; JAKMIP CC3 domain
  22. NM_001392054.1NP_001378983.1  janus kinase and microtubule-interacting protein 3 isoform m

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Conserved Domains (2) summary
    TIGR02168
    Location:27748
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:358553
    JAKMIP_CC3; JAKMIP CC3 domain
  23. NM_001392055.1NP_001378984.1  janus kinase and microtubule-interacting protein 3 isoform n

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Conserved Domains (2) summary
    TIGR02168
    Location:27746
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:358553
    JAKMIP_CC3; JAKMIP CC3 domain
  24. NM_001392056.1NP_001378985.1  janus kinase and microtubule-interacting protein 3 isoform n

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Related
    ENSP00000499788.1, ENST00000659050.1
    Conserved Domains (2) summary
    TIGR02168
    Location:27746
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:358553
    JAKMIP_CC3; JAKMIP CC3 domain
  25. NM_001392057.1NP_001378986.1  janus kinase and microtubule-interacting protein 3 isoform n

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Conserved Domains (2) summary
    TIGR02168
    Location:27746
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:358553
    JAKMIP_CC3; JAKMIP CC3 domain
  26. NM_001392058.1NP_001378987.1  janus kinase and microtubule-interacting protein 3 isoform o

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Conserved Domains (2) summary
    TIGR02168
    Location:27745
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:355550
    JAKMIP_CC3; JAKMIP CC3 domain
  27. NM_001392059.1NP_001378988.1  janus kinase and microtubule-interacting protein 3 isoform p

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Conserved Domains (2) summary
    TIGR02168
    Location:27744
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:356551
    JAKMIP_CC3; JAKMIP CC3 domain
  28. NM_001392060.1NP_001378989.1  janus kinase and microtubule-interacting protein 3 isoform p

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Related
    ENSP00000499227.1, ENST00000653623.1
    Conserved Domains (2) summary
    TIGR02168
    Location:27744
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:356551
    JAKMIP_CC3; JAKMIP CC3 domain
  29. NM_001392061.1NP_001378990.1  janus kinase and microtubule-interacting protein 3 isoform q

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Related
    ENSP00000499650.1, ENST00000661339.1
    Conserved Domains (2) summary
    TIGR02168
    Location:55734
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:347542
    JAKMIP_CC3; JAKMIP CC3 domain
  30. NM_001392062.1NP_001378991.1  janus kinase and microtubule-interacting protein 3 isoform q

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Related
    ENSP00000499348.1, ENST00000658847.1
    Conserved Domains (2) summary
    TIGR02168
    Location:55734
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:347542
    JAKMIP_CC3; JAKMIP CC3 domain
  31. NM_001392063.1NP_001378992.1  janus kinase and microtubule-interacting protein 3 isoform r

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Conserved Domains (2) summary
    TIGR02168
    Location:27732
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:358553
    JAKMIP_CC3; JAKMIP CC3 domain
  32. NM_001392064.1NP_001378993.1  janus kinase and microtubule-interacting protein 3 isoform r

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Conserved Domains (2) summary
    TIGR02168
    Location:27732
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:358553
    JAKMIP_CC3; JAKMIP CC3 domain
  33. NM_001392065.1NP_001378994.1  janus kinase and microtubule-interacting protein 3 isoform s

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Related
    ENSP00000499432.1, ENST00000669493.1
    Conserved Domains (2) summary
    TIGR02168
    Location:27722
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:356551
    JAKMIP_CC3; JAKMIP CC3 domain
  34. NM_001392066.1NP_001378995.1  janus kinase and microtubule-interacting protein 3 isoform t

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Conserved Domains (2) summary
    TIGR02168
    Location:27719
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:358524
    JAKMIP_CC3; JAKMIP CC3 domain
  35. NM_001392067.1NP_001378996.1  janus kinase and microtubule-interacting protein 3 isoform u

    Status: VALIDATED

    Source sequence(s)
    AL162274, AL512622
    Related
    ENSP00000499400.1, ENST00000670443.1
    Conserved Domains (2) summary
    TIGR02168
    Location:1660
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:273468
    JAKMIP_CC3; JAKMIP CC3 domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    132036068..132184858
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011539676.2XP_011537978.1  janus kinase and microtubule-interacting protein 3 isoform X1

    See identical proteins and their annotated locations for XP_011537978.1

    Conserved Domains (2) summary
    TIGR02168
    Location:27831
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:430625
    JAKMIP_CC3; JAKMIP CC3 domain
  2. XM_017016095.2XP_016871584.1  janus kinase and microtubule-interacting protein 3 isoform X1

    Conserved Domains (2) summary
    TIGR02168
    Location:27831
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:430625
    JAKMIP_CC3; JAKMIP CC3 domain
  3. XM_005252674.5XP_005252731.1  janus kinase and microtubule-interacting protein 3 isoform X2

    Conserved Domains (2) summary
    TIGR02168
    Location:27830
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:430625
    JAKMIP_CC3; JAKMIP CC3 domain
  4. XM_011539682.3XP_011537984.1  janus kinase and microtubule-interacting protein 3 isoform X3

    Conserved Domains (2) summary
    TIGR02168
    Location:27759
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:358553
    JAKMIP_CC3; JAKMIP CC3 domain
  5. XM_005252676.5XP_005252733.1  janus kinase and microtubule-interacting protein 3 isoform X4

    Conserved Domains (2) summary
    TIGR02168
    Location:27757
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam16034
    Location:356551
    JAKMIP_CC3; JAKMIP CC3 domain
  6. XM_017016098.2XP_016871587.1  janus kinase and microtubule-interacting protein 3 isoform X7

  7. XM_017016099.2XP_016871588.1  janus kinase and microtubule-interacting protein 3 isoform X8

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001104947.1: Suppressed sequence

    Description
    NM_001104947.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
  2. NM_194303.1: Suppressed sequence

    Description
    NM_194303.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
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