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Trpc7 transient receptor potential cation channel, subfamily C, member 7 [ Rattus norvegicus (Norway rat) ]

Gene ID: 282822, updated on 23-May-2018
Official Symbol
Trpc7provided by RGD
Official Full Name
transient receptor potential cation channel, subfamily C, member 7provided by RGD
Primary source
RGD:628820
See related
Ensembl:ENSRNOG00000012727
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
non-selective cation channel; activated down-stream of G-protein-coupled receptors [RGD, Feb 2006]
Expression
Biased expression in Brain (RPKM 10.1), Lung (RPKM 6.4) and 9 other tissues See more
Orthologs
See Trpc7 in Genome Data Viewer
Location:
17p14
Exon count:
14
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (8134267..8280360)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 17 NC_005116.3 (10316554..10456609)

Chromosome 17 - NC_005116.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108348498 Neighboring gene uncharacterized LOC103694032 Neighboring gene uncharacterized LOC108348499 Neighboring gene uncharacterized LOC102555284 Neighboring gene SMAD family member 5 Neighboring gene uncharacterized LOC102555503 Neighboring gene transforming growth factor, beta induced

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
calcium channel activity ISO
Inferred from Sequence Orthology
more info
 
cation channel activity TAS
Traceable Author Statement
more info
PubMed 
inositol 1,4,5 trisphosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
store-operated calcium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
calcium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
calcium ion transport ISO
Inferred from Sequence Orthology
more info
 
manganese ion transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
manganese ion transport ISO
Inferred from Sequence Orthology
more info
 
regulation of cytosolic calcium ion concentration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
single fertilization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
colocalizes_with cis-Golgi network IDA
Inferred from Direct Assay
more info
PubMed 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
short transient receptor potential channel 7
Names
capacitative calcium channel TRPC7
NP_001178620.2
XP_017455951.1
XP_017455952.1
XP_017455953.1
XP_017455954.1
XP_017455955.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191691.2NP_001178620.2  short transient receptor potential channel 7

    See identical proteins and their annotated locations for NP_001178620.2

    Status: VALIDATED

    Source sequence(s)
    AAHX01089877, AAHX01089878, AAHX01089879, AAHX01089880, AAHX01089881, AAHX01089882
    UniProtKB/TrEMBL
    F1LQF7
    Related
    ENSRNOP00000016982.4, ENSRNOT00000016982.4
    Conserved Domains (5) summary
    cd00204
    Location:51184
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    TIGR00870
    Location:27822
    trp; transient-receptor-potential calcium channel protein
    pfam08344
    Location:198256
    TRP_2; Transient receptor ion channel II
    sd00045
    Location:77108
    ANK; ANK repeat [structural motif]
    cl00511
    Location:582665
    FTSW_RODA_SPOVE; Cell cycle protein

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005116.4 Reference Rnor_6.0 Primary Assembly

    Range
    8134267..8280360
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017600462.1XP_017455951.1  short transient receptor potential channel 7 isoform X1

  2. XM_017600463.1XP_017455952.1  short transient receptor potential channel 7 isoform X2

  3. XM_017600464.1XP_017455953.1  short transient receptor potential channel 7 isoform X3

  4. XM_017600465.1XP_017455954.1  short transient receptor potential channel 7 isoform X4

  5. XM_017600466.1XP_017455955.1  short transient receptor potential channel 7 isoform X5

Alternate Rn_Celera

Genomic

  1. AC_000085.1 Alternate Rn_Celera

    Range
    7806368..7928485
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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