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Sbsn suprabasin [ Mus musculus (house mouse) ]

Gene ID: 282619, updated on 12-May-2024

Summary

Official Symbol
Sbsnprovided by MGI
Official Full Name
suprabasinprovided by MGI
Primary source
MGI:MGI:2446326
See related
Ensembl:ENSMUSG00000046056 AllianceGenome:MGI:2446326
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110005D19Rik
Summary
Located in cytoplasm. Is expressed in several structures, including alimentary system; nose; and skin. Orthologous to human SBSN (suprabasin). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in placenta adult (RPKM 17.4), stomach adult (RPKM 9.3) and 15 other tissues See more
Orthologs
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Genomic context

See Sbsn in Genome Data Viewer
Location:
7 B1; 7 19.24 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (30432099..30455559)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (30732674..30756134)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E9108 Neighboring gene ATPase, H+/K+ exchanging, gastric, alpha polypeptide Neighboring gene STARR-positive B cell enhancer ABC_E11349 Neighboring gene transmembrane protein 147 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase, spermatogenic Neighboring gene dermokine Neighboring gene keratinocyte differentiation associated protein

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
suprabasin
Names
suprabasal-specific protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083903.1NP_001077372.1  suprabasin isoform 2 precursor

    See identical proteins and their annotated locations for NP_001077372.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The resulting protein (isoform 2) is shorter than isoform 1 and lacks the repetitive central domain rich in glycine and alanine found in isoform 1.
    Source sequence(s)
    AI507307, BC051531
    Consensus CDS
    CCDS59725.1
    UniProtKB/TrEMBL
    A0A0R4J2A5, S4R2I1
    Related
    ENSMUSP00000138561.2, ENSMUST00000182229.8
  2. NM_172205.3NP_757342.2  suprabasin isoform 1 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). The protein contains a repetitive central domain rich in glycine and alanine.
    Source sequence(s)
    AA791703, AC167978, AI507307
    Consensus CDS
    CCDS39891.1
    UniProtKB/TrEMBL
    E9QPB2
    Related
    ENSMUSP00000079362.6, ENSMUST00000080518.14
    Conserved Domains (1) summary
    pfam05262
    Location:462600
    Borrelia_P83; Borrelia P83/100 protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    30432099..30455559
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030242650.1XP_030098510.1  suprabasin isoform X1

    UniProtKB/TrEMBL
    E9QPB2
    Conserved Domains (1) summary
    pfam05262
    Location:462600
    Borrelia_P83; Borrelia P83/100 protein
  2. XM_006540028.3XP_006540091.1  suprabasin isoform X2

    Conserved Domains (1) summary
    pfam05262
    Location:452590
    Borrelia_P83; Borrelia P83/100 protein
  3. XM_006540029.2XP_006540092.1  suprabasin isoform X3

  4. XM_030242652.1XP_030098512.1  suprabasin isoform X4

    UniProtKB/TrEMBL
    A0A0R4J2A5, S4R2I1
  5. XM_030242651.1XP_030098511.1  suprabasin isoform X1

    UniProtKB/TrEMBL
    E9QPB2
    Conserved Domains (1) summary
    pfam05262
    Location:462600
    Borrelia_P83; Borrelia P83/100 protein