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CSTF2 cleavage stimulation factor subunit 2 [ Bos taurus (domestic cattle) ]

Gene ID: 282588, updated on 5-Sep-2025
Official Symbol
CSTF2provided by VGNC
Official Full Name
cleavage stimulation factor subunit 2provided by VGNC
Primary source
VGNC:VGNC:27781
See related
BGD:BT28616; EnsemblRapid:ENSBTAG00070034251
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
CSFT64; cstF-64
Orthologs
human mouse all
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See CSTF2 in Genome Data Viewer
Location:
chromosome: X
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) X NC_037357.1 (51349641..51381484, complement)

Chromosome X - NC_037357.1Genomic Context describing neighboring genes Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene transfer RNA glutamic acid (anticodon UUC) Neighboring gene NADPH oxidase 1 Neighboring gene synaptotagmin like 4 Neighboring gene uncharacterized LOC132344272

Genomic Sequence:
NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. The gene CSTF2T, encoding the human variant CstF-64 polyadenylation protein tauCstF-64, lacks introns and may be associated with male sterility. Dass B, et al. Genomics, 2002 Nov. PMID 12408968
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Clone Names

  • MGC142429

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables mRNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA 3'-end processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of mRNA cleavage and polyadenylation specificity factor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
cleavage stimulation factor subunit 2
Names
CF-1 64 kDa subunit
CSTF 64 kDa subunit
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174685.2 → NP_777110.1  cleavage stimulation factor subunit 2

    See identical proteins and their annotated locations for NP_777110.1

    Status: PROVISIONAL

    Source sequence(s)
    AY130297
    UniProtKB/Swiss-Prot
    Q8HXM1
    UniProtKB/TrEMBL
    A0AAA9RX58
    Related
    ENSBTAP00070046996.1, ENSBTAT00070077145.1
    Conserved Domains (5) summary
    cd12671
    Location:18 → 92
    RRM_CSTF2_CSTF2T; RNA recognition motif in cleavage stimulation factor subunit 2 (CSTF2), cleavage stimulation factor subunit 2 tau variant (CSTF2T) and similar proteins
    pfam14304
    Location:528 → 568
    CSTF_C; Transcription termination and cleavage factor C-terminal
    pfam14327
    Location:113 → 191
    CSTF2_hinge; Hinge domain of cleavage stimulation factor subunit 2
    cl25887
    Location:4 → 369
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cl25983
    Location:392 → 449
    Rnc; dsRNA-specific ribonuclease [Transcription]

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037357.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    51349641..51381484 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059883290.1 → XP_059739273.1  cleavage stimulation factor subunit 2 isoform X1

    UniProtKB/TrEMBL
    A1A4I6, F1MVI1
    Related
    ENSBTAP00070047028.1, ENSBTAT00070077186.1

RNA

  1. XR_009493448.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8HXM1.1 GenPept UniProtKB/Swiss-Prot:Q8HXM1

Gene LinkOut

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