PAFAH1B3 platelet activating factor acetylhydrolase 1b catalytic subunit 3 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: PAFAH1B3provided by VGNC
Official Full Name: platelet activating factor acetylhydrolase 1b catalytic subunit 3provided by VGNC
Primary source: VGNC:VGNC:32551
See related: BGD:BT28637; Ensembl:ENSBTAG00000019787
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	18	NC_037345.1 (50978702..50981557)

Chromosome 18 - NC_037345.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

In conclusion, our results show that one of the catalytic subunits of PAFAH1B, namely PAFAH1B3, is present in bovine, oocytes and that it plays a functional role in spindle formation and meiotic progression during bovine oocyte maturation.
Title: Platelet-activating factor acetylhydrolase 1B3 (PAFAH1B3) is required for the formation of the meiotic spindle during in vitro oocyte maturation.

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General gene information

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Markers

PAFAH1B3 (e-PCR)
- UniSTS:278883

MARC_7033-7034:996687486:1 (e-PCR)
- UniSTS:269703

General protein information

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Preferred Names: platelet-activating factor acetylhydrolase IB subunit alpha1

Names: PAF acetylhydrolase 29 kDa subunit; PAF-AH 29 kDa subunit; PAF-AH subunit gamma; PAFAH subunit gamma; platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa); platelet-activating factor acetylhydrolase IB subunit gamma

NP_777090.1

EC 3.1.1.47

XP_059732501.1

EC 3.1.1.47

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_174665.2 → NP_777090.1 platelet-activating factor acetylhydrolase IB subunit alpha1

See identical proteins and their annotated locations for NP_777090.1

Status: PROVISIONAL

Source sequence(s)

D30789

UniProtKB/Swiss-Prot

Q0VCF0, Q29460

UniProtKB/TrEMBL

A0AAF7ABT5

Conserved Domains (1) summary

cd01820
Location:7 → 207

PAF_acetylesterase_like; PAF_acetylhydrolase (PAF-AH)_like subfamily of SGNH-hydrolases. Platelet-activating factor (PAF) and PAF-AH are key players in inflammation and in atherosclerosis. PAF-AH is a calcium independent phospholipase A2 which exhibits strong substrate ...