PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: PAFAH1B2provided by VGNC
Official Full Name: platelet activating factor acetylhydrolase 1b catalytic subunit 2provided by VGNC
Primary source: VGNC:VGNC:32550
See related: BGD:BT29005; EnsemblRapid:ENSBTAG00070029447
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: PAFAH1B2P68402
Orthologs: all
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Genomic context

Location:: chromosome: 15

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	15	NC_037342.1 (27831374..27860117)

Chromosome 15 - NC_037342.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

PAFAH1B2 (e-PCR)
- UniSTS:278882

Pafah1b2 (e-PCR), detects polymorphism
- UniSTS:144116

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables platelet-activating factor acetyltransferase activity	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: platelet-activating factor acetylhydrolase IB subunit alpha2

Names: PAF acetylhydrolase 30 kDa subunit; PAF-AH 30 kDa subunit; PAF-AH subunit beta; PAFAH subunit beta; platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa); platelet-activating factor acetylhydrolase IB subunit beta

NP_777089.1

EC 3.1.1.47

XP_059730554.1

EC 3.1.1.47

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_174664.2 → NP_777089.1 platelet-activating factor acetylhydrolase IB subunit alpha2

See identical proteins and their annotated locations for NP_777089.1

Status: PROVISIONAL

Source sequence(s)

D49678

UniProtKB/Swiss-Prot

P68401, Q3ZBB8

Related

ENSBTAP00070040837.1, ENSBTAT00070066913.1

Conserved Domains (1) summary

cd01820
Location:8 → 217

PAF_acetylesterase_like; PAF_acetylhydrolase (PAF-AH)_like subfamily of SGNH-hydrolases. Platelet-activating factor (PAF) and PAF-AH are key players in inflammation and in atherosclerosis. PAF-AH is a calcium independent phospholipase A2 which exhibits strong substrate ...