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Slco1a1 solute carrier organic anion transporter family, member 1a1 [ Mus musculus (house mouse) ]

Gene ID: 28248, updated on 16-Oct-2021

Summary

Official Symbol
Slco1a1provided by MGI
Official Full Name
solute carrier organic anion transporter family, member 1a1provided by MGI
Primary source
MGI:MGI:1351891
See related
Ensembl:ENSMUSG00000041698
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Oatp1; OATP-1; Oatp1a1; Slc21a1; A530084B21
Expression
Biased expression in liver adult (RPKM 3.1) and liver E18 (RPKM 0.2) See more
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Genomic context

See Slco1a1 in Genome Data Viewer
Location:
6; 6 G2
Exon count:
14
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (141853007..141892688, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (141907281..141946962, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (141855802..141895483, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene solute carrier organic anion transporter family, member 1a4 Neighboring gene predicted gene, 30784 Neighboring gene predicted gene, 30843 Neighboring gene predicted gene 6614 Neighboring gene solute carrier organic anion transporter family, member 1a6 Neighboring gene predicted gene, 18159

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in bile acid and bile salt transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within ion transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within organic anion transport IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within response to stilbenoid IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in sodium-independent organic anion transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in basolateral plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
solute carrier organic anion transporter family member 1A1
Names
sodium-independent organic anion-transporting polypeptide 1
solute carrier family 21 (organic anion transporter), member 1
solute carrier family 21 member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013797.5NP_038825.1  solute carrier organic anion transporter family member 1A1

    See identical proteins and their annotated locations for NP_038825.1

    Status: VALIDATED

    Source sequence(s)
    AC156277, AF223067, BB848260
    Consensus CDS
    CCDS39691.1
    UniProtKB/Swiss-Prot
    Q9QXZ6
    UniProtKB/TrEMBL
    Q53ZW9
    Related
    ENSMUSP00000037022.6, ENSMUST00000042119.6
    Conserved Domains (3) summary
    cd06174
    Location:23396
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    cd01330
    Location:436488
    KAZAL_SLC21; The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a ...
    TIGR00805
    Location:1625
    oat; sodium-independent organic anion transporter

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    141853007..141892688 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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