SLC25A4 solute carrier family 25 member 4 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: SLC25A4provided by VGNC
Official Full Name: solute carrier family 25 member 4provided by VGNC
Primary source: VGNC:VGNC:34765
See related: BGD:BT12204; EnsemblRapid:ENSBTAG00070012155
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: ANT1
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 27

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	27	NC_037354.1 (15489566..15493429)

Chromosome 27 - NC_037354.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037354.1 Chromosome 27 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data show that the binding sites on adenine nucleotide translocator 1 (ANT1) have an affinity for cardiolipin (CL).
Title: Lipid-Loving ANTs: Molecular Simulations of Cardiolipin Interactions and the Organization of the Adenine Nucleotide Translocase in Model Mitochondrial Membranes.
Phosphatidic acid and cardiolipin interact with the mitochondrial ADP/ATP carrier.
Title: Association of phosphatidic acid with the bovine mitochondrial ADP/ATP carrier.
Crystal form of ADP/ATP carrier obtained in the presence of carboxyatractyloside was analysed.
Title: Structural basis for lipid-mediated interactions between mitochondrial ADP/ATP carrier monomers.

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General gene information

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Markers

SLC25A4 (e-PCR)
- UniSTS:279103

SLC25A4 (e-PCR)
- UniSTS:266054

BARC0064 (e-PCR)
- UniSTS:260472

G33947 (e-PCR)
- UniSTS:48256

MARC_5085-5086:996690129:1 (e-PCR)
- UniSTS:269452

SLC25A4 (e-PCR)
- UniSTS:519053

SLC25A4 (e-PCR)
- UniSTS:506255

A006N06 (e-PCR)
- UniSTS:58023

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP:ADP antiporter activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in mitochondrial ADP transmembrane transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in mitochondrial ATP transmembrane transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ADP/ATP translocase 1

Names: ADP,ATP carrier protein 1; ADP,ATP carrier protein, heart; ADP/ATP carrier; ADP/ATP translocase T1; ANT 1; adenine nucleotide translocator 1 (skeletal muscle)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.