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PRDX6 peroxiredoxin 6 [ Bos taurus (cattle) ]

Gene ID: 282438, updated on 27-Aug-2018

Summary

Official Symbol
PRDX6provided by VGNC
Official Full Name
peroxiredoxin 6provided by VGNC
Primary source
VGNC:VGNC:33304
See related
Ensembl:ENSBTAG00000004855
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
AOP2
Orthologs

Genomic context

See PRDX6 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
5
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 16 NC_037343.1 (54932648..54942564)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 16 AC_000173.1 (56389804..56399723)

Chromosome 16 - NC_037343.1Genomic Context describing neighboring genes Neighboring gene chromosome 16 C1orf158 homolog Neighboring gene arylacetamide deacetylase like 3 Neighboring gene U2 spliceosomal RNA Neighboring gene solute carrier family 9 member C2 (putative) Neighboring gene putative 60S ribosomal protein L32' Neighboring gene ankyrin repeat domain 45 Neighboring gene testis expressed 50

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

General gene information

Markers

Homology

Clone Names

  • KIAA0106

Gene Ontology Provided by GOA

Function Evidence Code Pubs
calcium-independent phospholipase A2 activity IEA
Inferred from Electronic Annotation
more info
 
glutathione peroxidase activity IEA
Inferred from Electronic Annotation
more info
 
peroxidase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
peroxiredoxin activity IEA
Inferred from Electronic Annotation
more info
 
phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) IEA
Inferred from Electronic Annotation
more info
 
phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 
ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cell redox homeostasis IEA
Inferred from Electronic Annotation
more info
 
cellular oxidant detoxification IEA
Inferred from Electronic Annotation
more info
 
glycerophospholipid catabolic process IEA
Inferred from Electronic Annotation
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 
response to reactive oxygen species ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
cytosol ISS
Inferred from Sequence or Structural Similarity
more info
 
lysosome IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
peroxiredoxin-6
Names
1-Cys PRX
1-Cys peroxiredoxin
NSGPx
PHGPx
acidic calcium-independent phospholipase A2
aiPLA2
anti-oxidant protein 2 (non-selenium glutathione peroxidase, acidic calcium-independent phospholipase A2)
antioxidant protein 2
calcium-independent phospholipase A2
ciliary body glutathione peroxidase
non-selenium glutathione peroxidase
NP_777068.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174643.1NP_777068.1  peroxiredoxin-6

    See identical proteins and their annotated locations for NP_777068.1

    Status: PROVISIONAL

    Source sequence(s)
    AF090194
    UniProtKB/Swiss-Prot
    O77834
    Related
    ENSBTAP00000006383.5, ENSBTAT00000006383.5
    Conserved Domains (1) summary
    cd03016
    Location:7222
    PRX_1cys; Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by ...

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037343.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    54932648..54942564
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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