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IFNAR2 interferon alpha and beta receptor subunit 2 [ Bos taurus (domestic cattle) ]

Gene ID: 282258, updated on 5-Sep-2025
Official Symbol
IFNAR2provided by VGNC
Official Full Name
interferon alpha and beta receptor subunit 2provided by VGNC
Primary source
VGNC:VGNC:30055
See related
BGD:BT10881; EnsemblRapid:ENSBTAG00070003177
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
IFN-R; IFNBR; IFN-R-2
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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See IFNAR2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 1 NC_037328.1 (2315591..2350080, complement)

Chromosome 1 - NC_037328.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104970778 Neighboring gene interleukin 10 receptor subunit beta Neighboring gene histone H4 Neighboring gene small ribosomal subunit protein uS15-like

Genomic Sequence:
NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Specific activation of embryonic IFNAR1 and endometrial IFNAR2 induced by embryonic IFNτ directs normal uterine fate for bovine early implantation. Wang X, et al. J Reprod Immunol, 2022 Sep. PMID 35907379
  2. Molecular cloning of ovine and bovine type I interferon receptor subunits from uteri, and endometrial expression of messenger ribonucleic acid for ovine receptors during the estrous cycle and pregnancy. Han CS, et al. Endocrinology, 1997 Nov. PMID 9348203
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Specific activation of embryonic IFNAR1 and endometrial IFNAR2 induced by embryonic IFNtau directs normal uterine fate for bovine early implantation.
    Title: Specific activation of embryonic IFNAR1 and endometrial IFNAR2 induced by embryonic IFNτ directs normal uterine fate for bovine early implantation.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables interleukin-22 receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables type I interferon receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in type I interferon-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
interferon alpha/beta receptor 2
Names
IFN-alpha-REC
IFN-alpha/beta receptor 2
interferon (alpha, beta and omega) receptor 2
interferon, beta; receptor
interferon-alpha/beta receptor beta chain
type I interferon receptor 2

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174553.2 → NP_776978.1  interferon alpha/beta receptor 2 precursor

    See identical proteins and their annotated locations for NP_776978.1

    Status: PROVISIONAL

    Source sequence(s)
    U75304
    UniProtKB/Swiss-Prot
    Q95141
    UniProtKB/TrEMBL
    A0AAA9SSG1
    Related
    ENSBTAP00070004334.1, ENSBTAT00070007325.1
    Conserved Domains (3) summary
    pfam01056
    Location:330 → 427
    Myc_N; Myc amino-terminal region
    pfam01108
    Location:24 → 120
    Tissue_fac; Tissue factor
    pfam09294
    Location:133 → 231
    Interfer-bind; Interferon-alpha/beta receptor, fibronectin type III

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037328.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    2315591..2350080 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q95141.1 GenPept UniProtKB/Swiss-Prot:Q95141

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials