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FLT3LG fms related receptor tyrosine kinase 3 ligand [ Bos taurus (domestic cattle) ]

Gene ID: 282233, updated on 5-Sep-2025
Official Symbol
FLT3LGprovided by VGNC
Official Full Name
fms related receptor tyrosine kinase 3 ligandprovided by VGNC
Primary source
VGNC:VGNC:29043
See related
BGD:BT30117; EnsemblRapid:ENSBTAG00070035298
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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See FLT3LG in Genome Data Viewer
Location:
chromosome: 18
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (55929632..55939492)

Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene golgi associated olfactory signaling regulator Neighboring gene solute carrier family 17 member 7 Neighboring gene PIH1 domain containing 1 Neighboring gene aldehyde dehydrogenase 16 family member A1 Neighboring gene small nucleolar RNA Z195/SNORD33/SNORD32 family Neighboring gene small nucleolar RNA Z195/SNORD33/SNORD32 family Neighboring gene ribosomal protein L13a

Genomic Sequence:
NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Identification of fetal liver tyrosine kinase 3 (flt3) ligand domain required for receptor binding and function using naturally occurring ligand isoforms. Mwangi W, et al. J Immunol, 2000 Dec 15. PMID 11120823
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables receptor tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
fms-related tyrosine kinase 3 ligand
Names
fms related tyrosine kinase 3 ligand
fms-like tyrosine kinase 3 ligand

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_181030.2 → NP_851373.1  fms-related tyrosine kinase 3 ligand precursor

    See identical proteins and their annotated locations for NP_851373.1

    Status: PROVISIONAL

    Source sequence(s)
    AF282985
    UniProtKB/TrEMBL
    F6RZ26, Q9GKE0
    Related
    ENSBTAP00070048127.1, ENSBTAT00070079218.1
    Conserved Domains (1) summary
    pfam02947
    Location:30 → 160
    Flt3_lig; flt3 ligand

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    55929632..55939492
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005219164.5 → XP_005219221.1  fms-related tyrosine kinase 3 ligand isoform X1

    See identical proteins and their annotated locations for XP_005219221.1

    UniProtKB/TrEMBL
    F6RZ26, Q8WNW1
    Conserved Domains (1) summary
    pfam02947
    Location:30 → 160
    Flt3_lig; flt3 ligand

  2. XM_005219163.5 → XP_005219220.1  fms-related tyrosine kinase 3 ligand isoform X1

    See identical proteins and their annotated locations for XP_005219220.1

    UniProtKB/TrEMBL
    F6RZ26, Q8WNW1
    Conserved Domains (1) summary
    pfam02947
    Location:30 → 160
    Flt3_lig; flt3 ligand

  3. XM_005219166.5 → XP_005219223.1  fms-related tyrosine kinase 3 ligand isoform X2

    See identical proteins and their annotated locations for XP_005219223.1

    UniProtKB/TrEMBL
    A2VE24, Q9GKD9
    Conserved Domains (1) summary
    pfam02947
    Location:30 → 142
    Flt3_lig; flt3 ligand
Nucleotide Protein Strain
Heading Accession and Version

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