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FCGR2B Fc gamma receptor IIb [ Bos taurus (domestic cattle) ]

Gene ID: 282229, updated on 5-Sep-2025
Gene symbol
FCGR2B
Gene description
Fc gamma receptor IIb
See related
EnsemblRapid:ENSBTAG00070004105
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
CD32; FCGR2; fcRII
Orthologs
human all
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See FCGR2B in Genome Data Viewer
Location:
chromosome: 3
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (7931199..7947703, complement)

Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene Fc receptor like B Neighboring gene Fc receptor like A Neighboring gene polyhomeotic-like protein 1 Neighboring gene microRNA mir-2285t Neighboring gene Fc fragment of IgG, low affinity IIIa, receptor (CD16a) Neighboring gene transfer RNA asparagine (anticodon GUU)

Genomic Sequence:
NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Fcγ Receptor IIB Controls Skin Inflammation in an Active Model of Epidermolysis Bullosa Acquisita. Kovacs B, et al. Front Immunol, 2019. PMID 31993051, Free PMC Article
  2. Cattle Fc gamma RII: molecular cloning and ligand specificity. Zhang G, et al. Immunogenetics, 1994. PMID 8188320
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Fcgamma Receptor IIB Controls Skin Inflammation in an Active Model of Epidermolysis Bullosa Acquisita.
    Title: Fcγ Receptor IIB Controls Skin Inflammation in an Active Model of Epidermolysis Bullosa Acquisita.
Submit: New GeneRIF Correction

Markers

Homology

Clone Names

  • MGC137852

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
low affinity immunoglobulin gamma Fc region receptor II-b
Names
Fc fragment of IgG receptor IIb
Fc fragment of IgG, low affinity IIb, receptor (CD32)
fc-gamma RII
igG Fc receptor II
low affinity immunoglobulin gamma Fc region receptor II

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174539.2 → NP_776964.1  low affinity immunoglobulin gamma Fc region receptor II-b precursor

    See identical proteins and their annotated locations for NP_776964.1

    Status: PROVISIONAL

    Source sequence(s)
    X75671
    UniProtKB/Swiss-Prot
    Q28110
    UniProtKB/TrEMBL
    A8DC35
    Conserved Domains (2) summary
    cd05752
    Location:49 → 127
    Ig1_FcgammaR_like; Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins
    cd05753
    Location:131 → 213
    Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    7931199..7947703 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005203449.5 → XP_005203506.1  low affinity immunoglobulin gamma Fc region receptor II-b isoform X6

    UniProtKB/TrEMBL
    A8DC35
    Conserved Domains (2) summary
    cd05753
    Location:131 → 213
    Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins
    cl11960
    Location:49 → 127
    Ig; Immunoglobulin domain

  2. XM_005203447.5 → XP_005203504.1  low affinity immunoglobulin gamma Fc region receptor II-b isoform X2

    UniProtKB/TrEMBL
    E1B9L0
    Conserved Domains (2) summary
    cd05752
    Location:49 → 127
    Ig1_FcgammaR_like; Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins
    cd05753
    Location:131 → 213
    Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins

  3. XM_010802739.4 → XP_010801041.1  low affinity immunoglobulin gamma Fc region receptor II-b isoform X5

    UniProtKB/TrEMBL
    A8DC35
    Conserved Domains (2) summary
    cd05753
    Location:132 → 214
    Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins
    cl11960
    Location:50 → 128
    Ig; Immunoglobulin domain

  4. XM_005203448.5 → XP_005203505.1  low affinity immunoglobulin gamma Fc region receptor II-b isoform X3

    UniProtKB/TrEMBL
    A8DC35
    Related
    ENSBTAP00070005151.1, ENSBTAT00070009286.1
    Conserved Domains (2) summary
    cd05752
    Location:50 → 128
    Ig1_FcgammaR_like; Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins
    cd05753
    Location:132 → 214
    Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins

  5. XM_005203446.5 → XP_005203503.1  low affinity immunoglobulin gamma Fc region receptor II-b isoform X1

    UniProtKB/TrEMBL
    E1B9L0, F1MHH9
    Related
    ENSBTAP00070005150.1, ENSBTAT00070009285.1
    Conserved Domains (2) summary
    cd05752
    Location:50 → 128
    Ig1_FcgammaR_like; Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins
    cd05753
    Location:132 → 214
    Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins

  6. XM_059881710.1 → XP_059737693.1  low affinity immunoglobulin gamma Fc region receptor II-b isoform X4

    UniProtKB/TrEMBL
    E1B9L0
    Related
    ENSBTAP00070005146.1, ENSBTAT00070009281.1

RNA

  1. XR_233812.5 RNA Sequence

  2. XR_805259.4 RNA Sequence

    Related
    ENSBTAT00070009283.1

  3. XR_003032514.2 RNA Sequence

  4. XR_805258.4 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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