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YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon [ Bos taurus (cattle) ]

Gene ID: 282125, updated on 2-Oct-2018

Summary

Official Symbol
YWHAEprovided by VGNC
Official Full Name
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilonprovided by VGNC
Primary source
VGNC:VGNC:37045
See related
BGD:BT17005; Ensembl:ENSBTAG00000005664
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs

Genomic context

See YWHAE in Genome Data Viewer
Location:
chromosome: 19
Exon count:
6
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 19 NC_037346.1 (22513993..22548938, complement)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 19 AC_000176.1 (23086221..23121185, complement)

Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104975006 Neighboring gene double C2 domain beta Neighboring gene uncharacterized LOC112442619 Neighboring gene transfer RNA glutamic acid (anticodon UUC) Neighboring gene CRK proto-oncogene, adaptor protein Neighboring gene geranylgeranyl transferase type-2 subunit beta-like

Genomic regions, transcripts, and products

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
calcium channel regulator activity IEA
Inferred from Electronic Annotation
more info
 
histone deacetylase binding IEA
Inferred from Electronic Annotation
more info
 
identical protein binding IEA
Inferred from Electronic Annotation
more info
 
ion channel binding IEA
Inferred from Electronic Annotation
more info
 
phosphoserine residue binding IEA
Inferred from Electronic Annotation
more info
 
potassium channel regulator activity IEA
Inferred from Electronic Annotation
more info
 
protein domain specific binding IEA
Inferred from Electronic Annotation
more info
 
protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
scaffold protein binding IEA
Inferred from Electronic Annotation
more info
 
ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
MAPK cascade ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to heat ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of calcium ion export across plasma membrane IEA
Inferred from Electronic Annotation
more info
 
negative regulation of calcium ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
negative regulation of peptidyl-serine dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of protein export from nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
protein localization to nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of cytosolic calcium ion concentration IEA
Inferred from Electronic Annotation
more info
 
regulation of membrane repolarization IEA
Inferred from Electronic Annotation
more info
 
regulation of potassium ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
melanosome IEA
Inferred from Electronic Annotation
more info
 
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
14-3-3 protein epsilon
Names
14-3-3E
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174491.3NP_776916.1  14-3-3 protein epsilon

    See identical proteins and their annotated locations for NP_776916.1

    Status: PROVISIONAL

    Source sequence(s)
    BC102928
    UniProtKB/Swiss-Prot
    P62261
    Related
    ENSBTAP00000007442.5, ENSBTAT00000007442.5
    Conserved Domains (1) summary
    cd10020
    Location:4233
    14-3-3_epsilon; 14-3-3 epsilon, an isoform of 14-3-3 protein

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037346.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    22513993..22548938 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005220066.3XP_005220123.1  14-3-3 protein epsilon isoform X2

    See identical proteins and their annotated locations for XP_005220123.1

    Conserved Domains (1) summary
    cd10020
    Location:4233
    14-3-3_epsilon; 14-3-3 epsilon, an isoform of 14-3-3 protein
  2. XM_024979616.1XP_024835384.1  14-3-3 protein epsilon isoform X1

    Conserved Domains (1) summary
    cd10020
    Location:4233
    14-3-3_epsilon; 14-3-3 epsilon, an isoform of 14-3-3 protein

RNA

  1. XR_003030582.1 RNA Sequence

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