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PDE6C phosphodiesterase 6C [ Bos taurus (domestic cattle) ]

Gene ID: 281975, updated on 17-Aug-2024

Summary

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Official Symbol
PDE6Cprovided by VGNC
Official Full Name
phosphodiesterase 6Cprovided by VGNC
Primary source
VGNC:VGNC:32681
See related
Ensembl:ENSBTAG00000000445
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 26
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 26 NC_037353.1 (14911696..14964881)

Chromosome 26 - NC_037353.1Genomic Context describing neighboring genes Neighboring gene free fatty acid receptor 4 Neighboring gene retinol binding protein 4 Neighboring gene FRA10A associated CGG repeat 1 Neighboring gene serpin B8-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037353.1 Chromosome 26 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of a noncatalytic cGMP-binding domain conserved in both the cGMP-stimulated and photoreceptor cyclic nucleotide phosphodiesterases. Charbonneau H, et al. Proc Natl Acad Sci U S A, 1990 Jan. PMID 2153290, Free PMC Article
  2. Bovine cone photoreceptor cGMP phosphodiesterase structure deduced from a cDNA clone. Li TS, et al. Proc Natl Acad Sci U S A, 1990 Jan. PMID 2153291, Free PMC Article
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3',5'-cyclic-nucleotide phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in visual perception IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'
Names
PDE V-C1
cGMP phosphodiesterase 6C
phosphodiesterase 6C, cGMP-specific, cone, alpha prime
phosphodiesterase, cyclic GMP (cone receptor)
NP_776844.1
XP_010818090.1
XP_059737714.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174419.1 → NP_776844.1  cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'

    See identical proteins and their annotated locations for NP_776844.1

    Status: PROVISIONAL

    Source sequence(s)
    M37838
    UniProtKB/Swiss-Prot
    P16586
    Related
    ENSBTAP00000000569.5, ENSBTAT00000000569.6
    Conserved Domains (2) summary
    smart00065
    Location:71 → 229
    GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
    pfam00233
    Location:556 → 801
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037353.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    14911696..14964881
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010819788.4 → XP_010818090.1  cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' isoform X1

    See identical proteins and their annotated locations for XP_010818090.1

    UniProtKB/TrEMBL
    E1BKB8
    Conserved Domains (2) summary
    smart00065
    Location:71 → 229
    GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
    pfam00233
    Location:556 → 801
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

  2. XM_059881731.1 → XP_059737714.1  cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' isoform X2

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P16586.1 GenPept UniProtKB/Swiss-Prot:P16586

Gene LinkOut

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Molecular Biology Databases
Research Materials