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NCALD neurocalcin delta [ Bos taurus (domestic cattle) ]

Gene ID: 281940, updated on 18-Aug-2024

Summary

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Official Symbol
NCALDprovided by VGNC
Official Full Name
neurocalcin deltaprovided by VGNC
Primary source
VGNC:VGNC:31897
See related
BGD:BT25495; Ensembl:ENSBTAG00000026963
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 14
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 14 NC_037341.1 (62246632..62715291)

Chromosome 14 - NC_037341.1Genomic Context describing neighboring genes Neighboring gene ubiquitin protein ligase E3 component n-recognin 5 Neighboring gene U6 spliceosomal RNA Neighboring gene ribonucleotide reductase regulatory TP53 inducible subunit M2B Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC101904656 Neighboring gene grainyhead like transcription factor 2 Neighboring gene transfer RNA tryptophan (anticodon CCA)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037341.1 Chromosome 14 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural, biochemical, and functional characterization of the calcium sensor neurocalcin delta in the inner retinal neurons and its linkage with the rod outer segment membrane guanylate cyclase transduction system. Krishnan A, et al. Biochemistry, 2004 Mar 16. PMID 15005606
  2. Crystal structure of recombinant bovine neurocalcin. Vijay-Kumar S, et al. Nat Struct Biol, 1999 Jan. PMID 9886296
  3. Crystallization and preliminary X-ray crystallographic studies of recombinant bovine neurocalcin delta. Kumar VD, et al. Proteins, 1996 Jun. PMID 8811741
  4. Calcium and membrane binding properties of bovine neurocalcin delta expressed in Escherichia coli. Ladant D. J Biol Chem, 1995 Feb 17. PMID 7852401
  5. Full sequence of neurocalcin, a novel calcium-binding protein abundant in central nervous system. Okazaki K, et al. Biochem Biophys Res Commun, 1992 May 29. PMID 1599450

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Neurocalcin delta modulates the Ca2+-modulated membrane guanylate cyclase transduction system in the neurons of the retinal inner plexiform layer.
    Title: Structural, biochemical, and functional characterization of the calcium sensor neurocalcin delta in the inner retinal neurons and its linkage with the rod outer segment membrane guanylate cyclase transduction system.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Clone Names

  • MGC139617

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tubulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in calcium-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neurocalcin-delta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001359911.1 → NP_001346840.1  neurocalcin-delta

    Status: VALIDATED

    Source sequence(s)
    DAAA02039339, DAAA02039341, DT899793, DV826731, EH144443, EH147775, EH153129, EH200876
    UniProtKB/Swiss-Prot
    A1L533, P61602, Q0IIL3
    Related
    ENSBTAP00000069878.1, ENSBTAT00000068404.1
    Conserved Domains (1) summary
    COG5126
    Location:14 → 179
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

  2. NM_001359912.1 → NP_001346841.1  neurocalcin-delta

    Status: VALIDATED

    Source sequence(s)
    DT899793, DV826731, EE227229, EH144443, EH147775, EH153129, EH200876, NKLS02000014
    UniProtKB/Swiss-Prot
    A1L533, P61602, Q0IIL3
    Conserved Domains (1) summary
    COG5126
    Location:14 → 179
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

  3. NM_174398.3 → NP_776823.1  neurocalcin-delta

    See identical proteins and their annotated locations for NP_776823.1

    Status: VALIDATED

    Source sequence(s)
    DT899793, DV826731, EH144443, EH147775, EH153129, EH200876, NKLS02000014
    UniProtKB/Swiss-Prot
    A1L533, P61602, Q0IIL3
    Conserved Domains (1) summary
    COG5126
    Location:14 → 179
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037341.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    62246632..62715291
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025001407.2 → XP_024857175.1  neurocalcin-delta isoform X1

    UniProtKB/Swiss-Prot
    A1L533, P61602, Q0IIL3
    Conserved Domains (1) summary
    COG5126
    Location:14 → 179
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

  2. XM_025001408.2 → XP_024857176.1  neurocalcin-delta isoform X1

    UniProtKB/Swiss-Prot
    A1L533, P61602, Q0IIL3
    Conserved Domains (1) summary
    COG5126
    Location:14 → 179
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

  3. XM_059893125.1 → XP_059749108.1  neurocalcin-delta isoform X1

    UniProtKB/Swiss-Prot
    A1L533, P61602, Q0IIL3

  4. XM_025001409.2 → XP_024857177.1  neurocalcin-delta isoform X1

    UniProtKB/Swiss-Prot
    A1L533, P61602, Q0IIL3
    Conserved Domains (1) summary
    COG5126
    Location:14 → 179
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

  5. XM_025001406.2 → XP_024857174.1  neurocalcin-delta isoform X1

    UniProtKB/Swiss-Prot
    A1L533, P61602, Q0IIL3
    Conserved Domains (1) summary
    COG5126
    Location:14 → 179
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

  6. XM_015474513.3 → XP_015329999.1  neurocalcin-delta isoform X1

    UniProtKB/Swiss-Prot
    A1L533, P61602, Q0IIL3
    Conserved Domains (1) summary
    COG5126
    Location:14 → 179
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

  7. XM_005215613.5 → XP_005215670.1  neurocalcin-delta isoform X1

    See identical proteins and their annotated locations for XP_005215670.1

    UniProtKB/Swiss-Prot
    A1L533, P61602, Q0IIL3
    Conserved Domains (1) summary
    COG5126
    Location:14 → 179
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P61602.2 GenPept UniProtKB/Swiss-Prot:P61602

Gene LinkOut

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