EDNRB endothelin receptor type B [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: EDNRBprovided by VGNC
Official Full Name: endothelin receptor type Bprovided by VGNC
Primary source: VGNC:VGNC:28330
See related: BGD:BT10076; EnsemblRapid:ENSBTAG00070012281
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 12

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	12	NC_037339.1 (53038212..53067371, complement)

Chromosome 12 - NC_037339.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_037339.1 Chromosome 12 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Differential cell-specific and spatiotemporal expression of the EDN1 system and NOS in the bovine utero-placental unit may be associated with regulation of vascular and cellular functions during pregnancy.
Title: Placental expression and localization of endothelin-1 system and nitric oxide synthases during bovine pregnancy.
Elevated local expression of ET-1 and Ednra/Ednrb during the peri-ovulatory period induces the high contractile activity of the oviduct to optimize gamete transport.
Title: Endothelin-1 system in the bovine oviduct: a regulator of local contraction and gamete transport.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

EDNRB (e-PCR)
- UniSTS:253808

EDNRB-2 (e-PCR)
- UniSTS:253890

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables endothelin receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in developmental pigmentation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in endothelin receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in enteric nervous system development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of blood pressure	IEA Inferred from Electronic Annotation more info	PubMed
involved_in vasoconstriction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: endothelin receptor type B

Names: ET-B; ET-BR; endothelin B receptor; endothelin receptor non-selective type

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_174309.2 → NP_776734.1 endothelin receptor type B precursor

See identical proteins and their annotated locations for NP_776734.1

Status: PROVISIONAL

Source sequence(s)

D90456

UniProtKB/Swiss-Prot

P28088, Q0VCB3, Q9TSB9

Related

ENSBTAP00070016837.1, ENSBTAT00070027828.1

Conserved Domains (1) summary

cd15976
Location:101 → 396

7tmA_ET-BR; endothelin B receptor, member of the class A family of seven-transmembrane G protein-coupled receptors