UMPS uridine monophosphate synthetase [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: UMPSprovided by VGNC
Official Full Name: uridine monophosphate synthetaseprovided by VGNC
Primary source: VGNC:VGNC:36661
See related: BGD:BT12220; Ensembl:ENSBTAG00000013727
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	1	NC_037328.1 (69127829..69177876)

Chromosome 1 - NC_037328.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:: NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

UMPS (e-PCR)
- UniSTS:505540

UMPS (e-PCR)
- UniSTS:279242

D3S3488 (e-PCR)
- UniSTS:60394

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables orotate phosphoribosyltransferase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables orotidine-5'-phosphate decarboxylase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in 'de novo' UMP biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in 'de novo' pyrimidine nucleobase biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: uridine 5'-monophosphate synthase

Names: UMP synthase; mutant uridine monophosphate synthase; orotate phosphoribosyl transferase and orotidine-5'-decarboxylase; uridine monophophate synthase; uridine monophosphate synthase

NP_803474.1

EC 2.4.2.10

EC 4.1.1.23

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_177508.1 → NP_803474.1 uridine 5'-monophosphate synthase

See identical proteins and their annotated locations for NP_803474.1

Status: PROVISIONAL

Source sequence(s)

X65125

UniProtKB/Swiss-Prot

P31754, Q2KHV1

UniProtKB/TrEMBL

A0AAA9SBF5

Related

ENSBTAP00000091480.1, ENSBTAT00000129304.1

Conserved Domains (2) summary

pfam00215
Location:252 → 466

OMPdecase; Orotidine 5'-phosphate decarboxylase / HUMPS family

cl00309
Location:7 → 204

PRTases_typeI; Phosphoribosyl transferase (PRT)-type I domain