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Serp1 stress-associated endoplasmic reticulum protein 1 [ Mus musculus (house mouse) ]

Gene ID: 28146, updated on 11-Apr-2024

Summary

Official Symbol
Serp1provided by MGI
Official Full Name
stress-associated endoplasmic reticulum protein 1provided by MGI
Primary source
MGI:MGI:92638
See related
Ensembl:ENSMUSG00000027808 AllianceGenome:MGI:92638
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ramp4; D3Ucla1
Summary
Acts upstream of or within several processes, including endoplasmic reticulum unfolded protein response; positive regulation of organ growth; and positive regulation of peptide hormone secretion. Predicted to be located in cytoplasmic microtubule. Is expressed in several structures, including jaw and orbito-sphenoid. Orthologous to human SERP1 (stress associated endoplasmic reticulum protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 190.1), duodenum adult (RPKM 144.7) and 27 other tissues See more
Orthologs
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Genomic context

See Serp1 in Genome Data Viewer
Location:
3 D; 3 28.58 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (58429390..58433305, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (58521969..58525884, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E11710 Neighboring gene predicted gene, 20128 Neighboring gene TSC22 domain family, member 2 Neighboring gene STARR-seq mESC enhancer starr_07749 Neighboring gene STARR-positive B cell enhancer ABC_E1618 Neighboring gene STARR-positive B cell enhancer ABC_E516 Neighboring gene STARR-positive B cell enhancer ABC_E3433 Neighboring gene eukaryotic translation initiation factor 2A Neighboring gene STARR-seq mESC enhancer starr_07753 Neighboring gene STARR-seq mESC enhancer starr_07754 Neighboring gene STARR-positive B cell enhancer ABC_E9549 Neighboring gene selenoprotein T Neighboring gene glutamate rich 6 Neighboring gene predicted gene, 46806

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in cytoplasmic microtubule ISO
Inferred from Sequence Orthology
more info
 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
stress-associated endoplasmic reticulum protein 1
Names
ribosome associated membrane protein 4
ribosome-attached membrane protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030685.3NP_109610.1  stress-associated endoplasmic reticulum protein 1

    See identical proteins and their annotated locations for NP_109610.1

    Status: VALIDATED

    Source sequence(s)
    AI114944, AK149786, CV676503
    Consensus CDS
    CCDS38436.1
    UniProtKB/Swiss-Prot
    Q3TMC9, Q9Z1W5
    Related
    ENSMUSP00000029385.8, ENSMUST00000029385.9
    Conserved Domains (1) summary
    pfam06624
    Location:259
    RAMP4; Ribosome associated membrane protein RAMP4

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    58429390..58433305 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)