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RDH8 retinol dehydrogenase 8 [ Bos taurus (domestic cattle) ]

Gene ID: 281449, updated on 17-Aug-2024

Summary

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Official Symbol
RDH8provided by VGNC
Official Full Name
retinol dehydrogenase 8provided by VGNC
Primary source
VGNC:VGNC:52817
See related
BGD:BT29463; Ensembl:ENSBTAG00000010188
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (14589608..14596077)

Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene transfer RNA aspartic acid (anticodon GUC) Neighboring gene collagen type V alpha 3 chain Neighboring gene uncharacterized LOC132345693 Neighboring gene complement C3 Neighboring gene angiopoietin like 6 Neighboring gene shiftless antiviral inhibitor of ribosomal frameshifting

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification and characterization of all-trans-retinol dehydrogenase from photoreceptor outer segments, the visual cycle enzyme that reduces all-trans-retinal to all-trans-retinol. Rattner A, et al. J Biol Chem, 2000 Apr 14. PMID 10753906
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables estradiol 17-beta-dehydrogenase [NAD(P)+] activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in estrogen biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
retinol dehydrogenase 8
Names
photoreceptor outer segment all-trans retinol dehydrogenase
retinol dehydrogenase 8 (all-trans)
NP_776592.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174167.2 → NP_776592.1  retinol dehydrogenase 8

    See identical proteins and their annotated locations for NP_776592.1

    Status: PROVISIONAL

    Source sequence(s)
    AF229846
    UniProtKB/Swiss-Prot
    Q9N126
    UniProtKB/TrEMBL
    A0AAF6YUM7
    Related
    ENSBTAP00000013443.5, ENSBTAT00000013443.6
    Conserved Domains (2) summary
    cd09806
    Location:6 → 263
    type1_17beta-HSD-like_SDR_c; human estrogenic 17beta-hydroxysteroid dehydrogenase type 1 (type 1 17beta-HSD)-like, classical (c) SDRs
    pfam00106
    Location:6 → 201
    adh_short; short chain dehydrogenase

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    14589608..14596077
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9N126.1 GenPept UniProtKB/Swiss-Prot:Q9N126

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials