RDH8 retinol dehydrogenase 8 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: RDH8provided by VGNC
Official Full Name: retinol dehydrogenase 8provided by VGNC
Primary source: VGNC:VGNC:52817
See related: BGD:BT29463; EnsemblRapid:ENSBTAG00070017267
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	7	NC_037334.1 (14589608..14596077)

Chromosome 7 - NC_037334.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:: NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables all-trans-retinol dehydrogenase (NAD+) activity	IEA Inferred from Electronic Annotation more info	PubMed
enables estradiol 17-beta-dehydrogenase [NAD(P)+] activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in estrogen biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in retinol metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: retinol dehydrogenase 8

Names: photoreceptor outer segment all-trans retinol dehydrogenase; retinol dehydrogenase 8 (all-trans)

NP_776592.1

EC 1.1.1.300

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_174167.2 → NP_776592.1 retinol dehydrogenase 8

See identical proteins and their annotated locations for NP_776592.1

Status: PROVISIONAL

Source sequence(s)

AF229846

UniProtKB/Swiss-Prot

Q9N126

UniProtKB/TrEMBL

A0AAF6YUM7

Related

ENSBTAP00070023076.1, ENSBTAT00070038919.1

Conserved Domains (2) summary

cd09806
Location:6 → 263

type1_17beta-HSD-like_SDR_c; human estrogenic 17beta-hydroxysteroid dehydrogenase type 1 (type 1 17beta-HSD)-like, classical (c) SDRs

pfam00106
Location:6 → 201

adh_short; short chain dehydrogenase