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MC2R melanocortin 2 receptor [ Bos taurus (domestic cattle) ]

Gene ID: 281299, updated on 5-Sep-2025
Official Symbol
MC2Rprovided by VGNC
Official Full Name
melanocortin 2 receptorprovided by VGNC
Primary source
VGNC:VGNC:31293
See related
BGD:BT10871; EnsemblRapid:ENSBTAG00070023526
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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See MC2R in Genome Data Viewer
Location:
chromosome: 24
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 24 NC_037351.1 (43564576..43583046, complement)

Chromosome 24 - NC_037351.1Genomic Context describing neighboring genes Neighboring gene RNA guanine-7 methyltransferase Neighboring gene melanocortin 5 receptor Neighboring gene uncharacterized LOC101902809 Neighboring gene glutamine synthetase pseudogene

Genomic Sequence:
NC_037351.1 Chromosome 24 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Molecular genetics of the ACTH and melanocyte-stimulating hormone receptors. Cone RD, et al. Trends Endocrinol Metab, 1993 Sep. PMID 18407163
  2. cDNA cloning and sequence analysis of the bovine adrenocorticotropic hormone (ACTH) receptor. Raikhinstein M, et al. Biochim Biophys Acta, 1994 Feb 17. PMID 8305507
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables corticotropin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
adrenocorticotropic hormone receptor
Names
ACTH receptor
ACTH-R
MC2-R
adrenocorticotropin receptor
melanocortin receptor 2

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174109.2 → NP_776534.1  adrenocorticotropic hormone receptor

    See identical proteins and their annotated locations for NP_776534.1

    Status: PROVISIONAL

    Source sequence(s)
    X74501
    UniProtKB/Swiss-Prot
    P34974
    Related
    ENSBTAP00070031852.1, ENSBTAT00070052993.1
    Conserved Domains (2) summary
    pfam00001
    Location:41 → 276
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:35 → 290
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037351.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    43564576..43583046 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34974.1 GenPept UniProtKB/Swiss-Prot:P34974

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.