Format

Send to:

Choose Destination

CDK1 cyclin dependent kinase 1 [ Bos taurus (cattle) ]

Gene ID: 281061, updated on 18-Apr-2019

Summary

Official Symbol
CDK1provided by VGNC
Official Full Name
cyclin dependent kinase 1provided by VGNC
Primary source
VGNC:VGNC:27115
See related
BGD:BT30042; Ensembl:ENSBTAG00000010109
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
CDC2
Orthologs

Genomic context

See CDK1 in Genome Data Viewer
Location:
chromosome: 28
Exon count:
11
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 28 NC_037355.1 (16488138..16538776)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 28 AC_000185.1 (16620119..16670633)

Chromosome 28 - NC_037355.1Genomic Context describing neighboring genes Neighboring gene ankyrin 3 Neighboring gene transfer RNA glycine (anticodon UCC) Neighboring gene U6 spliceosomal RNA Neighboring gene ferritin heavy chain pseudogene Neighboring gene Rho related BTB domain containing 1 Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 pseudogene

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

General gene information

Markers

Homology

Clone Names

  • MGC134454

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
Hsp70 protein binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II CTD heptapeptide repeat kinase activity IEA
Inferred from Electronic Annotation
more info
 
chromatin binding IEA
Inferred from Electronic Annotation
more info
 
cyclin binding IEA
Inferred from Electronic Annotation
more info
 
cyclin-dependent protein serine/threonine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
histone kinase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
Golgi disassembly ISS
Inferred from Sequence or Structural Similarity
more info
 
apoptotic process IEA
Inferred from Electronic Annotation
more info
 
cell division IEA
Inferred from Electronic Annotation
more info
 
cell proliferation IEA
Inferred from Electronic Annotation
more info
 
epithelial cell differentiation IEA
Inferred from Electronic Annotation
more info
 
histone phosphorylation IEA
Inferred from Electronic Annotation
more info
 
mitotic G2 DNA damage checkpoint IEA
Inferred from Electronic Annotation
more info
 
negative regulation of apoptotic process ISS
Inferred from Sequence or Structural Similarity
more info
 
peptidyl-serine phosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 
peptidyl-threonine phosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of G2/M transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 
positive regulation of mitochondrial ATP synthesis coupled electron transport IEA
Inferred from Electronic Annotation
more info
 
positive regulation of protein localization to nucleus IEA
Inferred from Electronic Annotation
more info
 
protein localization to kinetochore IEA
Inferred from Electronic Annotation
more info
 
regulation of circadian rhythm ISS
Inferred from Sequence or Structural Similarity
more info
 
rhythmic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
centrosome ISS
Inferred from Sequence or Structural Similarity
more info
 
cyclin B1-CDK1 complex IEA
Inferred from Electronic Annotation
more info
 
cytosol IEA
Inferred from Electronic Annotation
more info
 
midbody ISS
Inferred from Sequence or Structural Similarity
more info
 
mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
 
mitotic spindle ISS
Inferred from Sequence or Structural Similarity
more info
 
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
spindle microtubule ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
cyclin-dependent kinase 1
Names
cell division control protein 2 homolog
cell division cycle 2, G1 to S and G2 to M
cell division protein kinase 1
p34 protein kinase
NP_776441.1
XP_005226354.1
XP_005226356.1
XP_010818803.1
XP_024842276.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174016.2NP_776441.1  cyclin-dependent kinase 1

    See identical proteins and their annotated locations for NP_776441.1

    Status: PROVISIONAL

    Source sequence(s)
    L26547
    UniProtKB/Swiss-Prot
    P48734
    Related
    ENSBTAP00000013337.2, ENSBTAT00000013337.3
    Conserved Domains (2) summary
    PLN00009
    Location:1293
    PLN00009; cyclin-dependent kinase A; Provisional
    cd07861
    Location:3287
    STKc_CDK1_euk; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 1 from higher eukaryotes

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037355.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    16488138..16538776
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005226297.4XP_005226354.1  cyclin-dependent kinase 1 isoform X1

    See identical proteins and their annotated locations for XP_005226354.1

    UniProtKB/Swiss-Prot
    P48734
    Conserved Domains (1) summary
    cd07861
    Location:3287
    STKc_CDK1_euk; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 1 from higher eukaryotes
  2. XM_010820501.3XP_010818803.1  cyclin-dependent kinase 1 isoform X2

    See identical proteins and their annotated locations for XP_010818803.1

    Related
    ENSBTAP00000058343.1, ENSBTAT00000076563.1
    Conserved Domains (2) summary
    PLN00009
    Location:1267
    PLN00009; cyclin-dependent kinase A; Provisional
    cl21453
    Location:3267
    PKc_like; Protein Kinases, catalytic domain
  3. XM_024986508.1XP_024842276.1  cyclin-dependent kinase 1 isoform X3

    Conserved Domains (1) summary
    cl21453
    Location:3230
    PKc_like; Protein Kinases, catalytic domain
  4. XM_005226299.3XP_005226356.1  cyclin-dependent kinase 1 isoform X1

    See identical proteins and their annotated locations for XP_005226356.1

    UniProtKB/Swiss-Prot
    P48734
    Conserved Domains (1) summary
    cd07861
    Location:3287
    STKc_CDK1_euk; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 1 from higher eukaryotes
Support Center