CALR calreticulin [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: CALRprovided by VGNC
Official Full Name: calreticulinprovided by VGNC
Primary source: VGNC:VGNC:26715
See related: BGD:BT25069; EnsemblRapid:ENSBTAG00070015103
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	7	NC_037334.1 (12618114..12621944, complement)

Chromosome 7 - NC_037334.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Found in extracellular matrix where it may play an important role in mineralization.
Title: Calreticulin--an endoplasmic reticulum protein with calcium-binding activity is also found in the extracellular matrix.
the lectin site of CRT is the main target for gentamicin binding
Title: Gentamicin binds to the lectin site of calreticulin and inhibits its chaperone activity.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables unfolded protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein folding	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info	PubMed
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: calreticulin

Names: CRP55; HACBP; calrectulin; calregulin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.