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AMBP alpha-1-microglobulin/bikunin precursor [ Bos taurus (domestic cattle) ]

Gene ID: 280996, updated on 1-Feb-2025
Gene symbol
AMBP
Gene description
alpha-1-microglobulin/bikunin precursor
See related
BGD:BT24914; EnsemblRapid:ENSBTAG00070012357
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
all
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See AMBP in Genome Data Viewer
Location:
chromosome: 8
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 8 NC_037335.1 (103296350..103308504, complement)

Chromosome 8 - NC_037335.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101907033 Neighboring gene zinc finger protein 618 Neighboring gene kinesin family member 12 Neighboring gene collagen type XXVII alpha 1 chain Neighboring gene microRNA mir-455

Genomic Sequence:
NC_037335.1 Chromosome 8 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Kunitz-type proteinase inhibitors derived by limited proteolysis of the inter-alpha-trypsin inhibitor, VII. Characterization of the bovine inhibitor as double-headed trypsin-elastase inhibitor. Hochstrasser K, et al. Hoppe Seylers Z Physiol Chem, 1983 Dec. PMID 6199276
  2. Kunitz-type proteinase inhibitors derived by limited proteolysis of the inter-alpha-trypsin inhibitor, VII. Determination of the amino-acid sequence of the trypsin-released inhibitor from bovine inter-alpha-trypsin inhibitor. Hochstrasser K, et al. Hoppe Seylers Z Physiol Chem, 1983 Dec. PMID 6199275
  3. Identification of a factor in fetal bovine serum that stabilizes the cumulus extracellular matrix. A role for a member of the inter-alpha-trypsin inhibitor family. Chen L, et al. J Biol Chem, 1992 Jun 15. PMID 1376324
  4. Bovine alpha 1-microglobulin/bikunin. Isolation and characterization of liver cDNA and urinary alpha 1-microglobulin. Lindqvist A, et al. Biochim Biophys Acta, 1996 Apr 10. PMID 8611630
  5. Kunitz-type proteinase inhibitors derived by limited proteolysis of the inter-alpha-trypsin inhibitor, X. The amino-acid sequences of the trypsin-released inhibitors from horse and pig inter-alpha-trypsin inhibitors. Hochstrasser K, et al. Biol Chem Hoppe Seyler, 1985 May. PMID 2408637

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Clone Names

  • MGC128013

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
protein AMBP
Names
inter-alpha-trypsin inhibitor (protein HC), light
NP_776414.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173989.3 → NP_776414.1  protein AMBP precursor

    See identical proteins and their annotated locations for NP_776414.1

    Status: PROVISIONAL

    Source sequence(s)
    U35642
    UniProtKB/Swiss-Prot
    P00978, P35420, Q28020, Q3SZZ4
    UniProtKB/TrEMBL
    F1MMK9
    Related
    ENSBTAP00070017038.1, ENSBTAT00070028029.1
    Conserved Domains (3) summary
    pfam00014
    Location:231 → 282
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
    pfam00061
    Location:42 → 186
    Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family
    cl21528
    Location:12 → 48
    Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037335.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    103296350..103308504 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P00978.2 GenPept UniProtKB/Swiss-Prot:P00978

Gene LinkOut

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Molecular Biology Databases
Research Materials