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ACTB actin beta [ Bos taurus (cattle) ]

Gene ID: 280979, updated on 24-Dec-2022

Summary

Official Symbol
ACTBprovided by VGNC
Official Full Name
actin betaprovided by VGNC
Primary source
VGNC:VGNC:106628
See related
Ensembl:ENSBTAG00000026199
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
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Genomic context

See ACTB in Genome Data Viewer
Location:
chromosome: 25
Exon count:
6
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 25 NC_037352.1 (38799230..38802643)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 25 AC_000182.1 (39343633..39347047)

Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100196899 Neighboring gene transfer RNA glycine (anticodon UCC) Neighboring gene F-box and leucine rich repeat protein 18 Neighboring gene uncharacterized LOC107131848 Neighboring gene trinucleotide repeat containing 18

Genomic regions, transcripts, and products

Bibliography

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC128179

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables Tat protein binding IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding IEA
Inferred from Electronic Annotation
more info
 
enables kinesin binding IEA
Inferred from Electronic Annotation
more info
 
enables nitric-oxide synthase binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in adherens junction assembly IEA
Inferred from Electronic Annotation
more info
 
involved_in apical protein localization IEA
Inferred from Electronic Annotation
more info
 
involved_in cellular response to cytochalasin B IEA
Inferred from Electronic Annotation
more info
 
involved_in establishment or maintenance of cell polarity IEA
Inferred from Electronic Annotation
more info
 
involved_in histone H2A acetylation IEA
Inferred from Electronic Annotation
more info
 
involved_in histone H4 acetylation IEA
Inferred from Electronic Annotation
more info
 
involved_in morphogenesis of a polarized epithelium IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of protein binding IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 
involved_in postsynaptic actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 
involved_in protein localization to adherens junction IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of norepinephrine uptake IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of protein localization to plasma membrane IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of synaptic vesicle endocytosis IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transepithelial transport IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of NuA4 histone acetyltransferase complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in Schaffer collateral - CA1 synapse IEA
Inferred from Electronic Annotation
more info
 
located_in actin cytoskeleton ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
 
located_in apical junction complex IEA
Inferred from Electronic Annotation
more info
 
located_in brush border IEA
Inferred from Electronic Annotation
more info
 
located_in calyx of Held IEA
Inferred from Electronic Annotation
more info
 
located_in cortical cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasmic ribonucleoprotein granule IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cytosol TAS
Traceable Author Statement
more info
 
located_in dense body ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in focal adhesion ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 
located_in lamellipodium IEA
Inferred from Electronic Annotation
more info
 
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in postsynaptic actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
part_of protein-containing complex ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
located_in tight junction IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
actin, cytoplasmic 1
Names
beta-actin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173979.3NP_776404.2  actin, cytoplasmic 1

    See identical proteins and their annotated locations for NP_776404.2

    Status: PROVISIONAL

    Source sequence(s)
    BC102948
    UniProtKB/Swiss-Prot
    P60712, Q8MIJ0
    UniProtKB/TrEMBL
    A0A4W2DYQ2, A0A6B0SBF2
    Related
    ENSBTAP00000036739.5, ENSBTAT00000036888.5
    Conserved Domains (1) summary
    PTZ00281
    Location:1375
    PTZ00281; actin; Provisional

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037352.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    38799230..38802643
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)