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PRL prolactin [ Bos taurus (domestic cattle) ]

Gene ID: 280901, updated on 30-Jan-2025

Summary

Gene symbol
PRL
Gene description
prolactin
See related
BGD:BT12480; EnsemblRapid:ENSBTAG00070005386
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
GHA1; Prol
Annotation information
Annotation category: partial on reference assembly
Orthologs
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Genomic context

See PRL in Genome Data Viewer
Location:
chromosome: 23
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (35332693..35341308, complement)

Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene chorionic somatomammotropin hormone 1-like Neighboring gene chorionic somatomammotropin hormone 2 Neighboring gene HDGF like 1 Neighboring gene microRNA mir-2284c

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

Expression

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hormone activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables prolactin receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in female pregnancy IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in mammary gland development IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of lactation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in response to nutrient levels IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
prolactin
Names
growth hormone A1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173953.2NP_776378.2  prolactin precursor

    See identical proteins and their annotated locations for NP_776378.2

    Status: PROVISIONAL

    Source sequence(s)
    V00112
    UniProtKB/Swiss-Prot
    A6QLX8, P01239, Q29417, Q95112
    UniProtKB/TrEMBL
    A0A1Z2RPP2, A0AAA9TTN2
    Related
    ENSBTAP00070006963.1, ENSBTAT00070012295.1
    Conserved Domains (1) summary
    cd10288
    Location:32229
    prolactin_like; Prolactin (PRL or PRL1), chorionic somatomammotropin, and related pituitary gland hormones

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    35332693..35341308 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)