KNG1 kininogen 1 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: KNG1provided by VGNC
Official Full Name: kininogen 1provided by VGNC
Primary source: VGNC:VGNC:53586
See related: BGD:BT29203; EnsemblRapid:ENSBTAG00070028131
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: KNG; KNG2
Orthologs: all
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Genomic context

Location:: chromosome: 1

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	1	NC_037328.1 (80506964..80530772, complement)

Chromosome 1 - NC_037328.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Bradykini stimulates endothelial cell fatty acid oxidation by calmodulin-dependent kinase kinase -dependent activation of AMP-activated protein kinase (AMPK)
Title: Bradykinin stimulates endothelial cell fatty acid oxidation by CaMKK-dependent activation of AMPK.
Bradykinin, together with its precursor and tissue kallikrein, is continuously released into the vasculature of the isolated, perfused, lactating bovine udder.
Title: The release and vascular action of bradykinin in the isolated perfused bovine udder.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cysteine-type endopeptidase inhibitor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in negative regulation of blood coagulation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of endopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of cytosolic calcium ion concentration	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in blood microparticle	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: kininogen-1

Names: bradykinin; kininogen I; kininogen II; kininogen-2; thiol proteinase inhibitor

NP_001106748.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.