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HK1 hexokinase 1 [ Bos taurus (cattle) ]

Gene ID: 280817, updated on 27-Aug-2018

Summary

Official Symbol
HK1provided by VGNC
Official Full Name
hexokinase 1provided by VGNC
Primary source
VGNC:VGNC:29864
See related
Ensembl:ENSBTAG00000012380
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs

Genomic context

See HK1 in Genome Data Viewer
Location:
chromosome: 28
Exon count:
23
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 28 NC_037355.1 (25636401..25768161)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 28 AC_000185.1 (25851519..25925057)

Chromosome 28 - NC_037355.1Genomic Context describing neighboring genes Neighboring gene Suv3 like RNA helicase Neighboring gene uncharacterized LOC112444732 Neighboring gene hexokinase domain containing 1 Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene tachykinin receptor 2 Neighboring gene tetraspanin 15 Neighboring gene 40S ribosomal protein SA-like

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
glucose binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
carbohydrate phosphorylation IEA
Inferred from Electronic Annotation
more info
 
glucose 6-phosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 
hexose metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
hexokinase-1
Names
HK I
brain form hexokinase
hexokinase I
hexokinase type I
NP_001012686.1
XP_010818827.1
XP_024842269.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012668.2NP_001012686.1  hexokinase-1

    See identical proteins and their annotated locations for NP_001012686.1

    Status: VALIDATED

    Source sequence(s)
    NKLS02000028
    UniProtKB/TrEMBL
    Q5W5U3
    Related
    ENSBTAP00000044468.3, ENSBTAT00000047248.3
    Conserved Domains (3) summary
    PTZ00107
    Location:12460
    PTZ00107; hexokinase; Provisional
    pfam00349
    Location:469667
    Hexokinase_1; Hexokinase
    pfam03727
    Location:673907
    Hexokinase_2; Hexokinase

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037355.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    25636401..25768161
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024986501.1XP_024842269.1  hexokinase-1 isoform X1

    Conserved Domains (3) summary
    pfam00349
    Location:473671
    Hexokinase_1
    pfam03727
    Location:677911
    Hexokinase_2
    cl27242
    Location:26464
    Hexokinase_2
  2. XM_010820525.2XP_010818827.1  hexokinase-1 isoform X2

    Conserved Domains (3) summary
    PTZ00107
    Location:20459
    PTZ00107; hexokinase; Provisional
    pfam00349
    Location:468666
    Hexokinase_1; Hexokinase
    pfam03727
    Location:672906
    Hexokinase_2; Hexokinase
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