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Eif3b eukaryotic translation initiation factor 3, subunit B [ Mus musculus (house mouse) ]

Gene ID: 27979, updated on 8-Jan-2023

Summary

Official Symbol
Eif3bprovided by MGI
Official Full Name
eukaryotic translation initiation factor 3, subunit Bprovided by MGI
Primary source
MGI:MGI:106478
See related
Ensembl:ENSMUSG00000056076 AllianceGenome:MGI:106478
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PRT1; Eif3s9; D5Wsu45e; EIF3-ETA; EIF3-P110; EIF3-P116
Summary
Contributes to translation initiation factor activity. Involved in translational initiation. Part of eukaryotic translation initiation factor 3 complex, eIF3m. Is active in synapse. Is expressed in several structures, including central nervous system; extraembryonic component; and sensory organ. Orthologous to human EIF3B (eukaryotic translation initiation factor 3 subunit B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 106.5), ovary adult (RPKM 52.6) and 28 other tissues See more
Orthologs
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Genomic context

See Eif3b in Genome Data Viewer
Location:
5 G2; 5 78.97 cM
Exon count:
19
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (140405060..140429113)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (140419305..140443358)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene sorting nexin 8 Neighboring gene predicted gene, 30550 Neighboring gene microRNA 7038 Neighboring gene kinesin family member 19B Neighboring gene predicted gene, 38728 Neighboring gene carbohydrate sulfotransferase 12

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding ISO
Inferred from Sequence Orthology
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
contributes_to translation initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
contributes_to translation initiation factor activity IDA
Inferred from Direct Assay
more info
PubMed 
contributes_to translation initiation factor activity ISO
Inferred from Sequence Orthology
more info
 
enables translation initiation factor activity ISO
Inferred from Sequence Orthology
more info
 
enables translation initiation factor binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in IRES-dependent viral translational initiation ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of translational initiation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
 
involved_in translational initiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in translational initiation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in translational initiation ISO
Inferred from Sequence Orthology
more info
 
involved_in viral translational termination-reinitiation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasmic stress granule ISO
Inferred from Sequence Orthology
more info
 
part_of eukaryotic translation initiation factor 3 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of eukaryotic translation initiation factor 3 complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of eukaryotic translation initiation factor 3 complex ISO
Inferred from Sequence Orthology
more info
 
part_of eukaryotic translation initiation factor 3 complex, eIF3m IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in synapse EXP
Inferred from Experiment
more info
PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
eukaryotic translation initiation factor 3 subunit B
Names
eIF-3-eta
eIF3 p116
eukaryotic translation initiation factor 3 subunit 9
eukaryotic translation initiation factor 3, subunit 9 (eta)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133916.2NP_598677.1  eukaryotic translation initiation factor 3 subunit B

    See identical proteins and their annotated locations for NP_598677.1

    Status: PROVISIONAL

    Source sequence(s)
    AC131670
    Consensus CDS
    CCDS19819.1
    UniProtKB/Swiss-Prot
    Q8JZQ9, Q922K2
    Related
    ENSMUSP00000098076.4, ENSMUST00000100507.8
    Conserved Domains (4) summary
    PHA03249
    Location:26148
    PHA03249; DNA packaging tegument protein UL25; Provisional
    COG5354
    Location:297796
    COG5354; Uncharacterized protein, contains Trp-Asp (WD) repeat [General function prediction only]
    cd12278
    Location:173253
    RRM_eIF3B; RNA recognition motif in eukaryotic translation initiation factor 3 subunit B (eIF-3B) and similar proteins
    sd00039
    Location:365412
    7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    140405060..140429113
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)