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secA preprotein translocase subunit SecA [ Desulfovibrio vulgaris str. Hildenborough ]

Gene ID: 2796172, updated on 20-Aug-2016

Summary

Gene symbol
secA
Gene description
preprotein translocase subunit SecA
Locus tag
DVU0825
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Desulfovibrio vulgaris str. Hildenborough (strain: Hildenborough, old-name: Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough)
Lineage
Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales; Desulfovibrionaceae; Desulfovibrio
Also known as
azi; div

Genomic context

Sequence:
NC_002937.3 (913045..915546, complement)

NC_002937.3Genomic Context describing neighboring genes Neighboring gene tRNA Neighboring gene bifunctional ornithine acetyltransferase/N-acetylglutamate synthase Neighboring gene hypothetical protein Neighboring gene glycolate oxidase, iron-sulfur subunit Neighboring gene glycolate oxidase subunit GlcD

Bibliography

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

  • Bacterial secretion system, organism-specific biosystem (from KEGG)
    Bacterial secretion system, organism-specific biosystemGram-negative bacteria secrete a wide range of proteins whose functions include biogenesis of organelles, such as pilli and flagella, nutrient acquisition, virulence, and efflux of drugs and other to...
  • Bacterial secretion system, conserved biosystem (from KEGG)
    Bacterial secretion system, conserved biosystemGram-negative bacteria secrete a wide range of proteins whose functions include biogenesis of organelles, such as pilli and flagella, nutrient acquisition, virulence, and efflux of drugs and other to...
  • Protein export, organism-specific biosystem (from KEGG)
    Protein export, organism-specific biosystemThe protein export is the active transport of proteins from the cytoplasm to the exterior of the cell, or to the periplasmic compartment in Gram-negative bacteria. The sec dependent pathway is the ge...
  • Protein export, conserved biosystem (from KEGG)
    Protein export, conserved biosystemThe protein export is the active transport of proteins from the cytoplasm to the exterior of the cell, or to the periplasmic compartment in Gram-negative bacteria. The sec dependent pathway is the ge...
  • Quorum sensing, organism-specific biosystem (from KEGG)
    Quorum sensing, organism-specific biosystemQuorum sensing (QS) is a regulatory system that allows bacteria to share information about cell density and adjust gene expression accordingly. All QS bacteria produce and release chemical signal mol...
  • Quorum sensing, conserved biosystem (from KEGG)
    Quorum sensing, conserved biosystemQuorum sensing (QS) is a regulatory system that allows bacteria to share information about cell density and adjust gene expression accordingly. All QS bacteria produce and release chemical signal mol...
  • Sec (secretion) system, organism-specific biosystem (from KEGG)
    Sec (secretion) system, organism-specific biosystemStructural complex; Environmental information processing; Bacterial secretion system
  • Sec (secretion) system, conserved biosystem (from KEGG)
    Sec (secretion) system, conserved biosystemStructural complex; Environmental information processing; Bacterial secretion system

General protein information

Names
preprotein translocase subunit SecA
YP_010046.1
  • functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002937.3 Reference assembly

    Range
    913045..915546 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_010046.1 preprotein translocase subunit SecA [Desulfovibrio vulgaris str. Hildenborough]

    See identical proteins and their annotated locations for YP_010046.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q72DV4
    Conserved Domains (5) summary
    PRK12904
    Location:1833
    PRK12904; preprotein translocase subunit SecA; Reviewed
    pfam01043
    Location:233340
    SecA_PP_bind; SecA preprotein cross-linking domain
    pfam02810
    Location:815832
    SEC-C; SEC-C motif
    pfam07516
    Location:570774
    SecA_SW; SecA Wing and Scaffold domain
    cl21455
    Location:415532
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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