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cre cyclization recombinase [ Escherichia phage P1 ]

Gene ID: 2777477, updated on 3-Apr-2024
Gene symbol
cre
Gene description
cyclization recombinase
Locus tag
P1_gp003
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia phage P1 (isolate: mod749::IS5 c1.100 mutant, nat-host: Escherichia coli)
Lineage
Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Punavirus
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Sequence:
NC_005856.1 (436..1467)

NC_005856.1Genomic Context describing neighboring genes Neighboring gene cre associated function Neighboring gene C8 Neighboring gene recombination enhancement function

Genomic Sequence:
NC_005856.1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Synapsis of loxP sites by Cre recombinase. Ghosh K, et al. J Biol Chem, 2007 Aug 17. PMID 17573343
  2. Temporal and spatial regulation of CRE recombinase expression in gonadotrophin-releasing hormone neurones in the mouse. Wolfe A, et al. J Neuroendocrinol, 2008 Jul. PMID 18445125, Free PMC Article
  3. Targeted deletion of RANKL in M cell inducer cells by the Col6a1-Cre driver. Nagashima K, et al. Biochem Biophys Res Commun, 2017 Nov 4. PMID 28882590
  4. Hypoxia-inducible factor 1 activation from adipose protein 2-cre mediated knockout of von Hippel-Lindau gene leads to embryonic lethality. Zhang J, et al. Clin Exp Pharmacol Physiol, 2012 Feb. PMID 22150821, Free PMC Article
  5. Genome of bacteriophage P1. Łobocka MB, et al. J Bacteriol, 2004 Nov. PMID 15489417, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. This study demonstrates that Col6a1-Cre driver mice are as useful as Twist2-Cre driver mice for functional analyses of GALT-resident mesenchymal cells, including MCi cells.
    Title: Targeted deletion of RANKL in M cell inducer cells by the Col6a1-Cre driver.
  2. Cre-recombinase in aP2-Cre mice, showed strong Cre activity in the dorsal hindbrain region and vertebrae of E12.5 embryos.
    Title: Hypoxia-inducible factor 1 activation from adipose protein 2-cre mediated knockout of von Hippel-Lindau gene leads to embryonic lethality.
  3. The GnRH-CRETeR mouse can be used to study genes that may have distinct roles in reproductive physiology during the various developmental stages.
    Title: Temporal and spatial regulation of CRE recombinase expression in gonadotrophin-releasing hormone neurones in the mouse.
  4. Cre-mediated synapsis of loxP sites occurs with a high affinity and is pH-dependent; the crystal structures of a pre-cleavage Cre-loxP synaptic complex in a configuration representing the starting point in the recombination pathway were determined
    Title: Synapsis of loxP sites by Cre recombinase.
Submit: New GeneRIF Correction

Homology

regulatory

  • Loc: 1394-1399 regulatory_class = minus_35_signal
  • Loc: 1394-1425 regulatory_class = promoter , standard_name = Pc8
  • Loc: 1420-1425 regulatory_class = minus_10_signal
Preferred Names
site-specific integrase
YP_006472.1
  • 24 pct identical to 351 aa integrase-like protein of Pseudomonas sp. in GenBank Accession Number CAA67462; similar to other bacterial integrases-recombinases

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_005856.1 Reference assembly

    Range
    436..1467
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_006472.1 site-specific integrase [Escherichia phage P1]

    See identical proteins and their annotated locations for YP_006472.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P06956
    UniProtKB/TrEMBL
    A0A385AH54, A0AA96J2R0, B3Y8R6, Q71TG5
    Conserved Domains (1) summary
    cd00799
    Location:153 → 339
    INT_Cre_C; C-terminal catalytic domain of Cre recombinase (also called integrase)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
1NZB_A.1
1NZB_B.1
1NZB_E.1
1NZB_F.1
1OUQ_A.1
1OUQ_B.1
1OUQ_E.1
1OUQ_F.1
2CRX_A.1
2CRX_B.1
3MGV_A.1
3MGV_B.1
3MGV_C.1
3MGV_D.1
P06956.1

Gene LinkOut

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