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Gemin4 gem nuclear organelle associated protein 4 [ Mus musculus (house mouse) ]

Gene ID: 276919, updated on 4-May-2024

Summary

Official Symbol
Gemin4provided by MGI
Official Full Name
gem nuclear organelle associated protein 4provided by MGI
Primary source
MGI:MGI:2449313
See related
Ensembl:ENSMUSG00000049396 AllianceGenome:MGI:2449313
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4932415L08Rik
Summary
Predicted to enable ribonucleoprotein complex binding activity. Predicted to be involved in spliceosomal snRNP assembly. Predicted to be located in Cajal body; cytosol; and nucleolus. Predicted to be part of SMN complex. Is expressed in brain and spinal cord. Orthologous to human GEMIN4 (gem nuclear organelle associated protein 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 14.9), mammary gland adult (RPKM 7.7) and 28 other tissues See more
Orthologs
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Genomic context

See Gemin4 in Genome Data Viewer
Location:
11 B5; 11 45.92 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (76101397..76108398, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (76210571..76217572, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene VPS53 GARP complex subunit Neighboring gene predicted gene, 46252 Neighboring gene TLC domain containing 3A Neighboring gene STARR-positive B cell enhancer ABC_E8426 Neighboring gene STARR-seq mESC enhancer starr_30015 Neighboring gene diazepam binding inhibitor-like 5 Neighboring gene glyoxalase domain containing 4

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Gene trapped (1) 

General gene information

Markers

Clone Names

  • MGC28146

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ribonucleoprotein complex binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in spliceosomal snRNP assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in spliceosomal snRNP assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in Cajal body ISO
Inferred from Sequence Orthology
more info
 
part_of SMN complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of SMN complex ISO
Inferred from Sequence Orthology
more info
 
part_of SMN-Sm protein complex ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177367.3NP_796341.2  gem-associated protein 4

    See identical proteins and their annotated locations for NP_796341.2

    Status: VALIDATED

    Source sequence(s)
    AL591129
    Consensus CDS
    CCDS25061.1
    UniProtKB/TrEMBL
    Q3URX8, Q6P6L6
    Related
    ENSMUSP00000099558.5, ENSMUST00000102500.5

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    76101397..76108398 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)