Format

Send to:

Choose Destination

GNA15 G protein subunit alpha 15 [ Homo sapiens (human) ]

Gene ID: 2769, updated on 22-Aug-2020

Summary

Official Symbol
GNA15provided by HGNC
Official Full Name
G protein subunit alpha 15provided by HGNC
Primary source
HGNC:HGNC:4383
See related
Ensembl:ENSG00000060558 MIM:139314
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GNA16
Expression
Biased expression in esophagus (RPKM 28.1), bone marrow (RPKM 27.9) and 13 other tissues See more
Orthologs

Genomic context

See GNA15 in Genome Data Viewer
Location:
19p13.3
Exon count:
7
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (3136033..3163749)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (3136191..3163766)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene G protein subunit alpha 11 Neighboring gene ribosomal protein L35 pseudogene Neighboring gene GNA15 divergent transcript Neighboring gene Sharpr-MPRA regulatory region 13242 Neighboring gene sphingosine-1-phosphate receptor 4 Neighboring gene nicalin

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium.
GeneReviews: Not available

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
G protein-coupled receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G protein-coupled receptor binding IDA
Inferred from Direct Assay
more info
PubMed 
G-protein beta/gamma-subunit complex binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
GTP binding IEA
Inferred from Electronic Annotation
more info
 
GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
type 2A serotonin receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
heterotrimeric G-protein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
heterotrimeric G-protein complex NAS
Non-traceable Author Statement
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 
synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
guanine nucleotide-binding protein subunit alpha-15
Names
G-protein subunit alpha-16
epididymis secretory sperm binding protein
epididymis tissue protein Li 17E
g alpha-15
g alpha-16
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
guanine nucleotide-binding protein subunit alpha-16

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_002068.4NP_002059.3  guanine nucleotide-binding protein subunit alpha-15

    See identical proteins and their annotated locations for NP_002059.3

    Status: VALIDATED

    Source sequence(s)
    AC005262, BC013585, BQ015560
    Consensus CDS
    CCDS12104.1
    UniProtKB/Swiss-Prot
    P30679
    Related
    ENSP00000262958.2, ENST00000262958.4
    Conserved Domains (1) summary
    smart00275
    Location:22372
    G_alpha; G protein alpha subunit

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    3136033..3163749
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center