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GML glycosylphosphatidylinositol anchored molecule like [ Homo sapiens (human) ]

Gene ID: 2765, updated on 17-Jun-2019

Summary

Official Symbol
GMLprovided by HGNC
Official Full Name
glycosylphosphatidylinositol anchored molecule likeprovided by HGNC
Primary source
HGNC:HGNC:4375
See related
Ensembl:ENSG00000104499 MIM:602370
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LY6DL
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See GML in Genome Data Viewer
Location:
8q24.3
Exon count:
4
Annotation release Status Assembly Chr Location
109.20190607 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (142834801..142846851)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (143916217..143928262)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene LYNX1-SLURP2 readthrough Neighboring gene Ly6/neurotoxin 1 Neighboring gene lymphocyte antigen 6 family member D Neighboring gene zinc finger HIT-type containing 1 pseudogene 1 Neighboring gene CYP11B1 recombination region Neighboring gene cytochrome P450 family 11 subfamily B member 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of glycosylphosphatidylinositol anchored molecule like protein (GML) by siRNA inhibits HIV-1 replication in HeLa-derived TZM-bl cells PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
anchored component of membrane IEA
Inferred from Electronic Annotation
more info
 
extrinsic component of membrane TAS
Traceable Author Statement
more info
PubMed 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
glycosyl-phosphatidylinositol-anchored molecule-like protein
Names
GPI anchored molecule like protein
Glycosylphosphatidylinositol-anchored molecule-like protein
glycosylphosphatidylinositol anchored molecule like protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_002066.3NP_002057.1  glycosyl-phosphatidylinositol-anchored molecule-like protein precursor

    See identical proteins and their annotated locations for NP_002057.1

    Status: VALIDATED

    Source sequence(s)
    AC083841, D84290
    Consensus CDS
    CCDS6391.1
    UniProtKB/Swiss-Prot
    Q99445
    Related
    ENSP00000220940.1, ENST00000220940.1
    Conserved Domains (1) summary
    smart00134
    Location:29116
    LU; Ly-6 antigen / uPA receptor -like domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    142834801..142846851
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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