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guaB IMP dehydrogenase [ Methanococcus maripaludis S2 ]

Gene ID: 2761150, updated on 22-Oct-2024

Summary

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Gene symbol
guaB
Gene description
IMP dehydrogenase
Locus tag
MMP_RS00765
Gene type
protein coding
Organism
Methanococcus maripaludis S2 (strain: S2)
Lineage
Archaea; Methanobacteriati; Methanobacteriota; Methanomada group; Methanococci; Methanococcales; Methanococcaceae; Methanococcus
Old locus tag
MMP0133
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Genomic context

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Sequence:
NC_005791.1 (139445..140947, complement)

NC_005791.1Genomic Context describing neighboring genes Neighboring gene tyrosine decarboxylase MfnA Neighboring gene branched-chain-amino-acid transaminase Neighboring gene Sjogren's syndrome/scleroderma autoantigen 1 family protein Neighboring gene threonine synthase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_005791.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Complete genome sequence of the genetically tractable hydrogenotrophic methanogen Methanococcus maripaludis. Hendrickson EL, et al. J Bacteriol, 2004 Oct. PMID 15466049, Free PMC Article
  2. Two classes of bacterial IMPDHs according to their quaternary structures and catalytic properties. Alexandre T, et al. PLoS One, 2015. PMID 25706619, Free PMC Article
  3. The CBS subdomain of inosine 5'-monophosphate dehydrogenase regulates purine nucleotide turnover. Pimkin M, et al. Mol Microbiol, 2008 Apr. PMID 18312263, Free PMC Article
  4. Characteristics and crystal structure of bacterial inosine-5'-monophosphate dehydrogenase. Zhang R, et al. Biochemistry, 1999 Apr 13. PMID 10200156

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
IMP dehydrogenase
WP_011170077.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_005791.1 Reference assembly

    Range
    139445..140947 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_011170077.1 IMP dehydrogenase [Methanococcus maripaludis]

    See identical proteins and their annotated locations for WP_011170077.1

    UniProtKB/TrEMBL
    A0A2L1CAG7, Q6M0Y5
    Conserved Domains (3) summary
    PRK05567
    Location:13 → 497
    PRK05567; inosine 5'-monophosphate dehydrogenase; Reviewed
    cd00381
    Location:16 → 472
    IMPDH; IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine ...
    cd04601
    Location:101 → 210
    CBS_pair_IMPDH; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein. IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a key ...
Nucleotide Protein
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