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Abcf2 ATP-binding cassette, sub-family F member 2 [ Mus musculus (house mouse) ]

Gene ID: 27407, updated on 6-Jun-2024

Summary

Official Symbol
Abcf2provided by MGI
Official Full Name
ATP-binding cassette, sub-family F member 2provided by MGI
Primary source
MGI:MGI:1351657
See related
Ensembl:ENSMUSG00000028953 AllianceGenome:MGI:1351657
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Drr3; E430001O06; 0710005O05Rik
Summary
Predicted to enable ATP binding activity. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human ABCF2 (ATP binding cassette subfamily F member 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 70.0), thymus adult (RPKM 32.4) and 28 other tissues See more
Orthologs
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Genomic context

See Abcf2 in Genome Data Viewer
Location:
5 A3; 5 11.93 cM
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (24770339..24782465, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (24565341..24577467, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene ankyrin repeat and SOCS box-containing 10 Neighboring gene IQ motif containing with AAA domain 1 like Neighboring gene STARR-positive B cell enhancer ABC_E6314 Neighboring gene ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g pseudogene Neighboring gene chondroitin polymerizing factor 2 Neighboring gene microRNA 671

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Gene trapped (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 

General protein information

Preferred Names
ATP-binding cassette sub-family F member 2
Names
ATP-binding cassette, sub-family F (GCN20), member 2
developmentally regulated repeat element-containing transcript 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001190443.2NP_001177372.1  ATP-binding cassette sub-family F member 2 isoform 2

    See identical proteins and their annotated locations for NP_001177372.1

    Status: VALIDATED

    Source sequence(s)
    AC116136
    UniProtKB/TrEMBL
    Q3UVI9
    Conserved Domains (3) summary
    cd03221
    Location:90306
    ABCF_EF-3; ATP-binding cassette domain of elongation factor 3, subfamily F
    COG0488
    Location:87607
    Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]
    pfam12848
    Location:300370
    ABC_tran_Xtn; ABC transporter
  2. NM_001359205.2NP_001346134.1  ATP-binding cassette sub-family F member 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC116136
    Consensus CDS
    CCDS19125.1
    UniProtKB/Swiss-Prot
    Q3UA24, Q8C1S5, Q99LE6, Q9JL48
    UniProtKB/TrEMBL
    Q3UVI9
    Conserved Domains (1) summary
    COG0488
    Location:88608
    Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]
  3. NM_001429004.1NP_001415933.1  ATP-binding cassette sub-family F member 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC116136
    UniProtKB/Swiss-Prot
    Q3UA24, Q8C1S5, Q99LE6, Q9JL48
    UniProtKB/TrEMBL
    Q3UVI9
  4. NM_001429005.1NP_001415934.1  ATP-binding cassette sub-family F member 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC116136
    UniProtKB/Swiss-Prot
    Q3UA24, Q8C1S5, Q99LE6, Q9JL48
    UniProtKB/TrEMBL
    Q3UVI9
  5. NM_001429006.1NP_001415935.1  ATP-binding cassette sub-family F member 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC116136
    UniProtKB/TrEMBL
    Q3UVI9
  6. NM_001429007.1NP_001415936.1  ATP-binding cassette sub-family F member 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC116136
    UniProtKB/TrEMBL
    Q3UVI9
  7. NM_001429008.1NP_001415937.1  ATP-binding cassette sub-family F member 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC116136
    UniProtKB/TrEMBL
    Q3UVI9
  8. NM_001429009.1NP_001415938.1  ATP-binding cassette sub-family F member 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC116136
    UniProtKB/TrEMBL
    Q3UVI9
  9. NM_001429010.1NP_001415939.1  ATP-binding cassette sub-family F member 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC116136
    UniProtKB/TrEMBL
    Q3UVI9
  10. NM_001429011.1NP_001415940.1  ATP-binding cassette sub-family F member 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC116136
    UniProtKB/TrEMBL
    Q3UVI9
  11. NM_001429012.1NP_001415941.1  ATP-binding cassette sub-family F member 2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC116136
    UniProtKB/TrEMBL
    Q3UVI9
  12. NM_001429013.1NP_001415942.1  ATP-binding cassette sub-family F member 2 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC116136
    UniProtKB/TrEMBL
    Q3UVI9
  13. NM_013853.3NP_038881.1  ATP-binding cassette sub-family F member 2 isoform 1

    See identical proteins and their annotated locations for NP_038881.1

    Status: VALIDATED

    Source sequence(s)
    AC116136
    Consensus CDS
    CCDS19125.1
    UniProtKB/Swiss-Prot
    Q3UA24, Q8C1S5, Q99LE6, Q9JL48
    UniProtKB/TrEMBL
    Q3UVI9
    Related
    ENSMUSP00000030795.9, ENSMUST00000030795.10
    Conserved Domains (1) summary
    COG0488
    Location:88608
    Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    24770339..24782465 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006535727.4XP_006535790.1  ATP-binding cassette sub-family F member 2 isoform X1

    Conserved Domains (1) summary
    COG0488
    Location:88608
    Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]