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Mrpl15 mitochondrial ribosomal protein L15 [ Mus musculus (house mouse) ]

Gene ID: 27395, updated on 1-Mar-2024

Summary

Official Symbol
Mrpl15provided by MGI
Official Full Name
mitochondrial ribosomal protein L15provided by MGI
Primary source
MGI:MGI:1351639
See related
Ensembl:ENSMUSG00000033845 AllianceGenome:MGI:1351639
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
L15mt; Rpml7; MRP-L7; HSPC145; MRP-L15
Summary
Predicted to be a structural constituent of ribosome. Acts upstream of or within cellular response to leukemia inhibitory factor. Located in mitochondrion. Is expressed in several structures, including axial musculature; central nervous system; early conceptus; gonad; and liver. Orthologous to human MRPL15 (mitochondrial ribosomal protein L15). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 6.3), CNS E11.5 (RPKM 5.1) and 26 other tissues See more
Orthologs
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Genomic context

See Mrpl15 in Genome Data Viewer
Location:
1 A1; 1 1.79 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (4843432..4855949, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (4773198..4785750, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene transforming, acidic coiled-coil containing protein 3 pseudogene Neighboring gene pyruvate dehydrogenase (lipoamide) beta pseudogene Neighboring gene STARR-seq mESC enhancer starr_00039 Neighboring gene STARR-seq mESC enhancer starr_00040 Neighboring gene lysophospholipase 1 Neighboring gene predicted gene, 57794

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome ISA
Inferred from Sequence Alignment
more info
PubMed 
Component Evidence Code Pubs
part_of large ribosomal subunit IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
PubMed 
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of mitochondrial large ribosomal subunit ISA
Inferred from Sequence Alignment
more info
PubMed 
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
part_of mitochondrial large ribosomal subunit NAS
Non-traceable Author Statement
more info
PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
large ribosomal subunit protein uL15m
Names
39S ribosomal protein L15, mitochondrial
ribosomal protein, mitochondrial, L7
NP_001171129.1
NP_001407614.1
NP_079576.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177658.2NP_001171129.1  large ribosomal subunit protein uL15m isoform 1 precursor

    See identical proteins and their annotated locations for NP_001171129.1

    Status: VALIDATED

    Source sequence(s)
    AC102311, AC117576
    Consensus CDS
    CCDS48211.1
    UniProtKB/Swiss-Prot
    Q3UBN5, Q9CPP5, Q9CPR5, Q9CRH4
    Related
    ENSMUSP00000115512.2, ENSMUST00000156816.7
    Conserved Domains (1) summary
    pfam00828
    Location:52175
    Ribosomal_L27A; Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
  2. NM_001420685.1NP_001407614.1  large ribosomal subunit protein uL15m isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AC102311
    UniProtKB/TrEMBL
    A0A0A6YVP4
  3. NM_025300.5NP_079576.1  large ribosomal subunit protein uL15m isoform 2 precursor

    See identical proteins and their annotated locations for NP_079576.1

    Status: VALIDATED

    Source sequence(s)
    AC102311, AC117576
    Consensus CDS
    CCDS35504.1
    UniProtKB/Swiss-Prot
    Q9CPR5
    Related
    ENSMUSP00000114649.2, ENSMUST00000130201.8
    Conserved Domains (1) summary
    pfam00828
    Location:52175
    Ribosomal_L18e; Ribosomal protein L18e/L15

RNA

  1. NR_033530.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC102311, AC117576

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    4843432..4855949 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)