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Magel2 melanoma antigen, family L, 2 [ Mus musculus (house mouse) ]

Gene ID: 27385, updated on 11-Dec-2018

Summary

Official Symbol
Magel2provided by MGI
Official Full Name
melanoma antigen, family L, 2provided by MGI
Primary source
MGI:MGI:1351648
See related
Ensembl:ENSMUSG00000056972
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ns7; nM15; NDNL1; Mage-l2
Orthologs

Genomic context

See Magel2 in Genome Data Viewer
Location:
7 C; 7 34.37 cM
Exon count:
1
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (62376979..62381640)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (69521865..69526526)

Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 42395 Neighboring gene predicted gene, 32061 Neighboring gene necdin Neighboring gene makorin, ring finger protein, 3 Neighboring gene paternally expressed 12

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
ubiquitin-protein transferase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
Arp2/3 complex-mediated actin nucleation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of actin nucleation IGI
Inferred from Genetic Interaction
more info
PubMed 
protein K63-linked ubiquitination ISO
Inferred from Sequence Orthology
more info
 
regulation of circadian rhythm IMP
Inferred from Mutant Phenotype
more info
PubMed 
retrograde transport, endosome to Golgi ISO
Inferred from Sequence Orthology
more info
 
rhythmic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
endosome ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with retromer complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
MAGE-like protein 2
Names
melanoma antigen-like gene 2
necdin-like 1
protein nS7

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013779.2NP_038807.4  MAGE-like protein 2

    Status: VALIDATED

    Source sequence(s)
    AC156555
    Consensus CDS
    CCDS52264.1
    UniProtKB/Swiss-Prot
    Q9QZ04
    Related
    ENSMUSP00000079265.5, ENSMUST00000080403.6
    Conserved Domains (1) summary
    pfam01454
    Location:10591223
    MAGE; MAGE family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

    Range
    62376979..62381640
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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