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VMA9 H(+)-transporting V0 sector ATPase subunit e [ Saccharomyces cerevisiae S288C ]

Gene ID: 2732686, updated on 18-Sep-2024

Summary

Official Symbol
VMA9
Official Full Name
H(+)-transporting V0 sector ATPase subunit e
Primary source
SGD:S000028508
Locus tag
YCL005W-A
See related
AllianceGenome:SGD:S000028508; FungiDB:YCL005W-A; VEuPathDB:YCL005W-A
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
CWH36; LDB10
Summary
Enables ATPase-coupled ion transmembrane transporter activity. Involved in several processes, including cell wall mannoprotein biosynthetic process; cellular protein-containing complex assembly; and vacuolar acidification. Located in fungal-type vacuole membrane. Part of vacuolar proton-transporting V-type ATPase, V0 domain. Orthologous to human ATP6V0E1 (ATPase H+ transporting V0 subunit e1) and ATP6V0E2 (ATPase H+ transporting V0 subunit e2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See VMA9 in Genome Data Viewer
Location:
chromosome: III
Exon count:
3
Sequence:
Chromosome: III; NC_001135.5 (107023..107417)

Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene acetolactate synthase regulatory subunit Neighboring gene ubiquitin-binding ESCRT-I subunit protein STP22 Neighboring gene ncRNA Neighboring gene Ldb16p

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Process Evidence Code Pubs
involved_in cell wall mannoprotein biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein-containing complex assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein-containing complex assembly IPI
Inferred from Physical Interaction
more info
PubMed 
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in transmembrane transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in vacuolar acidification IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in vacuolar acidification IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in fungal-type vacuole membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
part_of proton-transporting V-type ATPase, V0 domain IEA
Inferred from Electronic Annotation
more info
 
located_in vacuolar membrane IEA
Inferred from Electronic Annotation
more info
 
part_of vacuolar proton-transporting V-type ATPase, V0 domain IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of vacuolar proton-transporting V-type ATPase, V0 domain IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in vacuole IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
H(+)-transporting V0 sector ATPase subunit e
NP_958835.1
  • Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex; essential for vacuolar acidification; interacts with the V-ATPase assembly factor Vma21p in the ER; involved in V0 biogenesis

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001135.5 Reference assembly

    Range
    107023..107417
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184518.1NP_958835.1  TPA: H(+)-transporting V0 sector ATPase subunit e [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_958835.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VR05, Q3E7B6
    UniProtKB/TrEMBL
    A6ZTH7, B3LU68, C8Z479, G2WA13
    Conserved Domains (1) summary
    pfam05493
    Location:663
    ATP_synt_H; ATP synthase subunit H