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VENTX VENT homeobox [ Homo sapiens (human) ]

Gene ID: 27287, updated on 23-Nov-2021

Summary

Official Symbol
VENTXprovided by HGNC
Official Full Name
VENT homeoboxprovided by HGNC
Primary source
HGNC:HGNC:13639
See related
Ensembl:ENSG00000151650 MIM:607158
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NA88A; HPX42B; VENTX2
Summary
This gene encodes a member of the Vent family of homeodomain proteins. The encoded protein may function as a transcriptional repressor and be involved in mesodermal patterning and hemopoietic stem cell maintenance. Multiple pseudogenes exist for this gene. A transcribed pseudogene located on chromosome X may lead to antigen production in certain melanomas. [provided by RefSeq, Jul 2008]
Expression
Broad expression in appendix (RPKM 1.9), spleen (RPKM 1.1) and 24 other tissues See more
Orthologs
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Genomic context

See VENTX in Genome Data Viewer
Location:
10q26.3
Exon count:
3
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (133237855..133241928)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (135051359..135055432)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene kinase non-catalytic C-lobe domain containing 1 Neighboring gene uncharacterized LOC105378573 Neighboring gene undifferentiated embryonic cell transcription factor 1 Neighboring gene MIR202 host gene Neighboring gene microRNA 202 Neighboring gene ADAM metallopeptidase domain 8

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC119910, MGC119911

General protein information

Preferred Names
homeobox protein VENTX
Names
VENT homeobox homolog
VENT-like homeobox 2
VENT-like homeobox protein 2
hemopoietic progenitor homeobox protein VENTX2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014468.4NP_055283.1  homeobox protein VENTX

    See identical proteins and their annotated locations for NP_055283.1

    Status: REVIEWED

    Source sequence(s)
    AL445199
    Consensus CDS
    CCDS7675.1
    UniProtKB/Swiss-Prot
    O95231
    Related
    ENSP00000357556.5, ENST00000325980.10
    Conserved Domains (1) summary
    pfam00046
    Location:95147
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    133237855..133241928
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017016073.1XP_016871562.1  homeobox protein VENTX isoform X1

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