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TEKT2 tektin 2 [ Homo sapiens (human) ]

Gene ID: 27285, updated on 17-Jun-2019

Summary

Official Symbol
TEKT2provided by HGNC
Official Full Name
tektin 2provided by HGNC
Primary source
HGNC:HGNC:11725
See related
Ensembl:ENSG00000092850 MIM:608953
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TEKTB1; TEKTIN-T; h-tektin-t
Summary
This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. This gene is expressed in the testis and its protein is localized to the flagella of the sperms, indicating that it may play a role in spermatogenesis. [provided by RefSeq, Jul 2008]
Expression
Biased expression in testis (RPKM 21.9), lung (RPKM 4.1) and 1 other tissue See more
Orthologs

Genomic context

See TEKT2 in Genome Data Viewer
Location:
1p34.3
Exon count:
11
Annotation release Status Assembly Chr Location
109.20190607 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (36084094..36088275)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (36549676..36553877)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene argonaute RISC catalytic component 3 Neighboring gene uncharacterized LOC105378647 Neighboring gene magnesium transporter 1 pseudogene Neighboring gene ADP-ribosylhydrolase like 2 Neighboring gene collagen type VIII alpha 2 chain

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cilium movement involved in cell motility IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
flagellated sperm motility IEA
Inferred from Electronic Annotation
more info
 
inner dynein arm assembly IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
microtubule IEA
Inferred from Electronic Annotation
more info
 
microtubule cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule organizing center ISS
Inferred from Sequence or Structural Similarity
more info
 
motile cilium IEA
Inferred from Electronic Annotation
more info
 
nucleus HDA PubMed 

General protein information

Preferred Names
tektin-2
Names
tektin 2 (testicular)
tektin-B1
testicular tektin B1-like protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014466.3NP_055281.2  tektin-2

    See identical proteins and their annotated locations for NP_055281.2

    Status: REVIEWED

    Source sequence(s)
    AL138787
    Consensus CDS
    CCDS401.1
    UniProtKB/Swiss-Prot
    Q9UIF3
    Related
    ENSP00000207457.3, ENST00000207457.8
    Conserved Domains (1) summary
    pfam03148
    Location:17395
    Tektin; Tektin family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    36084094..36088275
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005270753.2XP_005270810.1  tektin-2 isoform X1

    See identical proteins and their annotated locations for XP_005270810.1

    UniProtKB/Swiss-Prot
    Q9UIF3
    Conserved Domains (1) summary
    pfam03148
    Location:17395
    Tektin; Tektin family
  2. XM_011541258.3XP_011539560.1  tektin-2 isoform X1

    See identical proteins and their annotated locations for XP_011539560.1

    UniProtKB/Swiss-Prot
    Q9UIF3
    Conserved Domains (1) summary
    pfam03148
    Location:17395
    Tektin; Tektin family
  3. XM_017001055.1XP_016856544.1  tektin-2 isoform X1

    UniProtKB/Swiss-Prot
    Q9UIF3
    Conserved Domains (1) summary
    pfam03148
    Location:17395
    Tektin; Tektin family
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