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B3gnt6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 [ Mus musculus (house mouse) ]

Gene ID: 272411, updated on 8-Feb-2024

Summary

Official Symbol
B3gnt6provided by MGI
Official Full Name
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6provided by MGI
Primary source
MGI:MGI:3039603
See related
Ensembl:ENSMUSG00000074004 AllianceGenome:MGI:3039603
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Core3; Core-3
Summary
Predicted to enable UDP-glycosyltransferase activity and galactosyltransferase activity. Predicted to be involved in poly-N-acetyllactosamine biosynthetic process. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi membrane. Orthologous to human B3GNT6 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in colon adult (RPKM 47.3) and large intestine adult (RPKM 2.1) See more
Orthologs
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Genomic context

See B3gnt6 in Genome Data Viewer
Location:
7 E1; 7 53.63 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (97841622..97848682, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (98192415..98199475, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene calpain 5 Neighboring gene olfactory marker protein Neighboring gene STARR-positive B cell enhancer mm9_chr7:105326664-105326964 Neighboring gene STARR-seq mESC enhancer starr_19624 Neighboring gene predicted gene, 16938 Neighboring gene alkaline ceramidase 3 Neighboring gene STARR-seq mESC enhancer starr_19625 Neighboring gene STARR-seq mESC enhancer starr_19626 Neighboring gene STARR-positive B cell enhancer mm9_chr7:105457877-105458178 Neighboring gene STARR-seq mESC enhancer starr_19627 Neighboring gene tsukushi, small leucine rich proteoglycan

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in poly-N-acetyllactosamine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein O-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase
Names
BGnT-6
beta-1,3-Gn-T6
beta-1,3-N-acetylglucosaminyltransferase 6
beta3Gn-T6
core 3 synthase
NP_001074636.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081167.1NP_001074636.1  acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase

    See identical proteins and their annotated locations for NP_001074636.1

    Status: PROVISIONAL

    Source sequence(s)
    AC119880
    Consensus CDS
    CCDS40027.1
    UniProtKB/Swiss-Prot
    Q3USF0
    Related
    ENSMUSP00000095879.3, ENSMUST00000098278.4
    Conserved Domains (1) summary
    cl21608
    Location:126318
    Galactosyl_T; Galactosyltransferase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    97841622..97848682 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)