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Ddx24 DEAD box helicase 24 [ Mus musculus (house mouse) ]

Gene ID: 27225, updated on 26-Sep-2022

Summary

Official Symbol
Ddx24provided by MGI
Official Full Name
DEAD box helicase 24provided by MGI
Primary source
MGI:MGI:1351337
See related
Ensembl:ENSMUSG00000041645 AllianceGenome:MGI:1351337
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700055J08Rik; 2510027P10Rik
Summary
Predicted to enable several functions, including ATP binding activity; RNA binding activity; and RNA helicase activity. Predicted to be active in nucleolus. Orthologous to human DDX24 (DEAD-box helicase 24). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in cerebellum adult (RPKM 38.5), cortex adult (RPKM 31.2) and 28 other tissues See more
Orthologs
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Genomic context

See Ddx24 in Genome Data Viewer
Location:
12; 12 E
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (103374235..103392106, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (103407976..103425847, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene ankyrin repeat and SOCS box-containing 2 Neighboring gene predicted gene 15523 Neighboring gene OTU domain, ubiquitin aldehyde binding 2 Neighboring gene predicted gene, 53758 Neighboring gene interferon, alpha-inducible protein 27 like 2A Neighboring gene interferon, alpha-inducible protein 27

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (2) 
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
 
enables helicase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ATP-dependent RNA helicase DDX24
Names
DEAD (Asp-Glu-Ala-Asp) box polypeptide 24
DEAD box protein 24
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 13 (RNA helicase A)
NP_001152974.1
NP_001351091.1
NP_001351092.1
NP_065240.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159502.2NP_001152974.1  ATP-dependent RNA helicase DDX24 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC154347, BB006411, BC055317
    Consensus CDS
    CCDS49152.1
    UniProtKB/Swiss-Prot
    Q9ESV0
    UniProtKB/TrEMBL
    F8WJA0
    Related
    ENSMUSP00000105628.3, ENSMUST00000110001.4
    Conserved Domains (3) summary
    COG0513
    Location:238787
    SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
    pfam00271
    Location:619727
    Helicase_C; Helicase conserved C-terminal domain
    cl21455
    Location:241557
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  2. NM_001364162.1NP_001351091.1  ATP-dependent RNA helicase DDX24 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC154347
    Consensus CDS
    CCDS26129.1
    UniProtKB/Swiss-Prot
    Q7TM97
    Conserved Domains (1) summary
    COG0513
    Location:192741
    SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
  3. NM_001364163.1NP_001351092.1  ATP-dependent RNA helicase DDX24 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC154347
    Consensus CDS
    CCDS26129.1
    UniProtKB/Swiss-Prot
    Q7TM97
    Conserved Domains (1) summary
    COG0513
    Location:192741
    SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
  4. NM_020494.4NP_065240.2  ATP-dependent RNA helicase DDX24 isoform 2

    See identical proteins and their annotated locations for NP_065240.2

    Status: VALIDATED

    Source sequence(s)
    BB006411, BC043721, CJ141277
    Consensus CDS
    CCDS26129.1
    UniProtKB/Swiss-Prot
    Q7TM97, Q9ESV0
    Related
    ENSMUSP00000040890.8, ENSMUST00000044923.15
    Conserved Domains (1) summary
    COG0513
    Location:192741
    SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    103374235..103392106 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)