U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Eloa elongin A [ Mus musculus (house mouse) ]

Gene ID: 27224, updated on 7-May-2024

Summary

Official Symbol
Eloaprovided by MGI
Official Full Name
elongin Aprovided by MGI
Primary source
MGI:MGI:1351315
See related
Ensembl:ENSMUSG00000028668 AllianceGenome:MGI:1351315
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tceb3; 110kDa; Tceb3a
Summary
Predicted to be involved in regulation of transcription by RNA polymerase II and transcription elongation from RNA polymerase II promoter. Predicted to be located in site of DNA damage. Predicted to be part of transcription elongation factor complex. Is expressed in several structures, including genitourinary system. Orthologous to several human genes including ELOA (elongin A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 13.4), liver E14 (RPKM 12.2) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Eloa in Genome Data Viewer
Location:
4 68.34 cM; 4 D3
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (135730681..135748960, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (136003370..136021649, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1 Neighboring gene predicted gene 13007 Neighboring gene STARR-positive B cell enhancer ABC_E2129 Neighboring gene predicted gene, 57721 Neighboring gene STARR-positive B cell enhancer ABC_E2130 Neighboring gene ribosomal protein L11

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (2)  1 citation

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
elongin-A
Names
RNA polymerase II transcription factor SIII subunit A1
SIII p110
elongin 110 kDa subunit
transcription elongation factor B polypeptide 3

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013736.4NP_038764.2  elongin-A

    See identical proteins and their annotated locations for NP_038764.2

    Status: PROVISIONAL

    Source sequence(s)
    AL672076
    Consensus CDS
    CCDS18798.1
    UniProtKB/Swiss-Prot
    Q3UI38, Q80VB2, Q8CB77, Q9R0Q5
    Related
    ENSMUSP00000030427.6, ENSMUST00000030427.6
    Conserved Domains (2) summary
    cd00183
    Location:3776
    TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme
    pfam06881
    Location:565663
    Elongin_A; RNA polymerase II transcription factor SIII (Elongin) subunit A

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    135730681..135748960 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)