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GPR82 G protein-coupled receptor 82 [ Homo sapiens (human) ]

Gene ID: 27197, updated on 22-Sep-2022

Summary

Official Symbol
GPR82provided by HGNC
Official Full Name
G protein-coupled receptor 82provided by HGNC
Primary source
HGNC:HGNC:4533
See related
Ensembl:ENSG00000171657 MIM:300748; AllianceGenome:HGNC:4533
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
The protein encoded by this gene is an orphan G protein-coupled receptor of unknown function. The encoded protein is a member of a family of proteins that contain seven transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. [provided by RefSeq, Sep 2011]
Expression
Broad expression in lymph node (RPKM 1.4), appendix (RPKM 1.3) and 18 other tissues See more
Orthologs
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Genomic context

See GPR82 in Genome Data Viewer
Location:
Xp11.4
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (41724181..41730130)
110 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (41129121..41135070)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (41583434..41589383)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene calcium/calmodulin dependent serine protein kinase Neighboring gene RNA, 7SL, cytoplasmic 144, pseudogene Neighboring gene G protein-coupled receptor 34 Neighboring gene ribosomal protein S15a pseudogene 39 Neighboring gene RNA, U6 small nuclear 202, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
probable G-protein coupled receptor 82

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_016566.1 RefSeqGene

    Range
    5027..10976
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_080817.5NP_543007.1  probable G-protein coupled receptor 82

    See identical proteins and their annotated locations for NP_543007.1

    Status: VALIDATED

    Source sequence(s)
    AL627402, BC070180
    Consensus CDS
    CCDS14259.1
    UniProtKB/Swiss-Prot
    Q5VT13, Q96P67
    Related
    ENSP00000303549.4, ENST00000302548.5
    Conserved Domains (1) summary
    pfam00001
    Location:32308
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    41724181..41730130
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047441991.1XP_047297947.1  probable G-protein coupled receptor 82 isoform X1

    UniProtKB/Swiss-Prot
    Q5VT13
  2. XM_047441992.1XP_047297948.1  probable G-protein coupled receptor 82 isoform X1

    UniProtKB/Swiss-Prot
    Q5VT13

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    41129121..41135070
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)