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ZNF777 zinc finger protein 777 [ Homo sapiens (human) ]

Gene ID: 27153, updated on 26-Nov-2021

Summary

Official Symbol
ZNF777provided by HGNC
Official Full Name
zinc finger protein 777provided by HGNC
Primary source
HGNC:HGNC:22213
See related
Ensembl:ENSG00000196453 MIM:619298
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in ovary (RPKM 4.5), brain (RPKM 4.0) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF777 in Genome Data Viewer
Location:
7q36.1
Exon count:
8
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (149431363..149461062, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (149128454..149158153, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375559 Neighboring gene uncharacterized LOC101928733 Neighboring gene tRNA-Cys (anticodon GCA) 11-1 Neighboring gene zinc finger protein 746 Neighboring gene tRNA-Cys (anticodon GCA) 16-1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1285

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015694.3NP_056509.2  zinc finger protein 777

    See identical proteins and their annotated locations for NP_056509.2

    Status: VALIDATED

    Source sequence(s)
    AB033111, AC073314, BC023985, BX444270, DR763452
    Consensus CDS
    CCDS43675.1
    UniProtKB/Swiss-Prot
    Q9ULD5
    Related
    ENSP00000247930.4, ENST00000247930.5
    Conserved Domains (7) summary
    smart00349
    Location:285343
    KRAB; krueppel associated box
    COG5048
    Location:640826
    COG5048; FOG: Zn-finger [General function prediction only]
    PRK10263
    Location:6186
    PRK10263; DNA translocase FtsK; Provisional
    sd00017
    Location:696716
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:669686
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:546568
    zf-C2H2; Zinc finger, C2H2 type
    pfam12417
    Location:199255
    DUF3669; Zinc finger protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    149431363..149461062 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005249980.3XP_005250037.1  zinc finger protein 777 isoform X1

    Conserved Domains (8) summary
    cd07765
    Location:329368
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    smart00349
    Location:329387
    KRAB; krueppel associated box
    COG5048
    Location:684870
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:740760
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:713730
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:738760
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:752776
    zf-H2C2_2; Zinc-finger double domain
    pfam14353
    Location:681730
    CpXC; CpXC protein
  2. XM_011516055.2XP_011514357.1  zinc finger protein 777 isoform X2

    See identical proteins and their annotated locations for XP_011514357.1

    UniProtKB/Swiss-Prot
    Q9ULD5
    Conserved Domains (7) summary
    smart00349
    Location:285343
    KRAB; krueppel associated box
    COG5048
    Location:640826
    COG5048; FOG: Zn-finger [General function prediction only]
    PRK10263
    Location:6186
    PRK10263; DNA translocase FtsK; Provisional
    sd00017
    Location:696716
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:669686
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:546568
    zf-C2H2; Zinc finger, C2H2 type
    pfam12417
    Location:199255
    DUF3669; Zinc finger protein
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