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Brd8dc BRD8 domain containing [ Mus musculus (house mouse) ]

Gene ID: 271508, updated on 8-Feb-2024

Summary

Official Symbol
Brd8dcprovided by MGI
Official Full Name
BRD8 domain containingprovided by MGI
Primary source
MGI:MGI:3045347
See related
Ensembl:ENSMUSG00000049357 AllianceGenome:MGI:3045347
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4933408B17Rik
Summary
Predicted to be involved in histone acetylation. Predicted to be part of NuA4 histone acetyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E14 (RPKM 1.6), CNS E11.5 (RPKM 1.5) and 20 other tissues See more
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Genomic context

Location:
18 B1; 18 18.69 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (34712899..34730521, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (34579846..34597468, complement)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_44205 Neighboring gene STARR-seq mESC enhancer starr_44207 Neighboring gene wingless-type MMTV integration site family, member 8A Neighboring gene STARR-positive B cell enhancer mm9_chr18:34732422-34732722 Neighboring gene NME/NM23 family member 5 Neighboring gene bromodomain containing 8 Neighboring gene predicted gene, 41688 Neighboring gene STARR-positive B cell enhancer ABC_E4242 Neighboring gene CapStarr-seq enhancer MGSCv37_chr18:34784160-34784348 Neighboring gene STARR-positive B cell enhancer ABC_E963 Neighboring gene kinesin family member 20A Neighboring gene CDC23 cell division cycle 23

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General protein information

Preferred Names
uncharacterized protein LOC271508

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001358301.1NP_001345230.1  uncharacterized protein LOC271508 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC074335
    UniProtKB/TrEMBL
    Q8CDF1
    Conserved Domains (1) summary
    cl02556
    Location:146206
    Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
  2. NM_001358302.1NP_001345231.1  uncharacterized protein LOC271508 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC074335
    UniProtKB/TrEMBL
    Q8CDF1
    Conserved Domains (1) summary
    cd05507
    Location:146229
    Bromo_brd8_like; Bromodomain, brd8_like subgroup. In mammals, brd8 (bromodomain containing 8) interacts with the thyroid hormone receptor in a ligand-dependent fashion and enhances thyroid hormone-dependent activation from thyroid response elements. Brd8 is thought to be ...
  3. NM_177773.4NP_808441.2  uncharacterized protein LOC271508 isoform 1

    See identical proteins and their annotated locations for NP_808441.2

    Status: VALIDATED

    Source sequence(s)
    AC074335
    Consensus CDS
    CCDS37758.1
    UniProtKB/TrEMBL
    G3X9B4, Q8CDF1
    Related
    ENSMUSP00000054234.3, ENSMUST00000056932.9
    Conserved Domains (1) summary
    cd05507
    Location:160259
    Bromo_brd8_like; Bromodomain, brd8_like subgroup. In mammals, brd8 (bromodomain containing 8) interacts with the thyroid hormone receptor in a ligand-dependent fashion and enhances thyroid hormone-dependent activation from thyroid response elements. Brd8 is thought to be ...

RNA

  1. NR_152398.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC074335
    Related
    ENSMUST00000129566.2
  2. NR_152399.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC074335
  3. NR_152400.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC074335
  4. NR_152401.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC074335

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    34712899..34730521 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)