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PALD1 phosphatase domain containing paladin 1 [ Homo sapiens (human) ]

Gene ID: 27143, updated on 12-May-2019

Summary

Official Symbol
PALD1provided by HGNC
Official Full Name
phosphatase domain containing paladin 1provided by HGNC
Primary source
HGNC:HGNC:23530
See related
Ensembl:ENSG00000107719 MIM:614656
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PALD; KIAA1274
Expression
Ubiquitous expression in lung (RPKM 5.3), spleen (RPKM 4.7) and 24 other tissues See more
Orthologs

Genomic context

See PALD1 in Genome Data Viewer
Location:
10q22.1
Exon count:
24
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 10 NC_000010.11 (70458542..70568450)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (72238564..72328206)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 4E binding protein 2 Neighboring gene Sharpr-MPRA regulatory region 10859 Neighboring gene nodal growth differentiation factor Neighboring gene YY1 transcription factor pseudogene 1 Neighboring gene perforin 1 Neighboring gene Sharpr-MPRA regulatory region 11165

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1274

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein serine/threonine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein tyrosine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
peptidyl-tyrosine dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014431.3NP_055246.2  paladin

    See identical proteins and their annotated locations for NP_055246.2

    Status: VALIDATED

    Source sequence(s)
    AC022532, AL355344, BC040163, CN335744
    Consensus CDS
    CCDS31215.1
    UniProtKB/Swiss-Prot
    Q9ULE6
    UniProtKB/TrEMBL
    A0A024QZM5
    Related
    ENSP00000263563.5, ENST00000263563.7
    Conserved Domains (1) summary
    pfam14566
    Location:161330
    PTPlike_phytase; Inositol hexakisphosphate

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p12 Primary Assembly

    Range
    70458542..70568450
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011539638.2XP_011537940.1  paladin isoform X1

    See identical proteins and their annotated locations for XP_011537940.1

    UniProtKB/Swiss-Prot
    Q9ULE6
    UniProtKB/TrEMBL
    A0A024QZM5
    Conserved Domains (1) summary
    pfam14566
    Location:161330
    PTPlike_phytase; Inositol hexakisphosphate
  2. XM_011539637.2XP_011537939.1  paladin isoform X1

    See identical proteins and their annotated locations for XP_011537939.1

    UniProtKB/Swiss-Prot
    Q9ULE6
    UniProtKB/TrEMBL
    A0A024QZM5
    Conserved Domains (1) summary
    pfam14566
    Location:161330
    PTPlike_phytase; Inositol hexakisphosphate
  3. XM_017016072.1XP_016871561.1  paladin isoform X1

    UniProtKB/Swiss-Prot
    Q9ULE6
    UniProtKB/TrEMBL
    A0A024QZM5
    Conserved Domains (1) summary
    pfam14566
    Location:161330
    PTPlike_phytase; Inositol hexakisphosphate

RNA

  1. XR_001747093.1 RNA Sequence

  2. XR_945675.2 RNA Sequence

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