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CLUL1 clusterin like 1 [ Homo sapiens (human) ]

Gene ID: 27098, updated on 26-Oct-2022

Summary

Official Symbol
CLUL1provided by HGNC
Official Full Name
clusterin like 1provided by HGNC
Primary source
HGNC:HGNC:2096
See related
Ensembl:ENSG00000079101 MIM:616990; AllianceGenome:HGNC:2096
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RA337M
Summary
Predicted to enable misfolded protein binding activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in prostate (RPKM 1.3), thyroid (RPKM 0.8) and 10 other tissues See more
Orthologs
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Genomic context

See CLUL1 in Genome Data Viewer
Location:
18p11.32
Exon count:
16
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 18 NC_000018.10 (596988..650182)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 18 NC_060942.1 (751354..804514)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (596988..650182)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene RN7SK pseudogene 146 Neighboring gene centrin 1 Neighboring gene Sharpr-MPRA regulatory region 12053 Neighboring gene uncharacterized LOC105371952 Neighboring gene TYMS opposite strand RNA Neighboring gene enolase superfamily member 1 Neighboring gene thymidylate synthetase Neighboring gene YES proto-oncogene 1, Src family tyrosine kinase Neighboring gene RNA, U1 small nuclear 109, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables misfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
clusterin-like protein 1
Names
clusterin-like 1 (retinal)
retinal clusterin-like protein
retinal-specific clusterin-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001289036.3NP_001275965.2  clusterin-like protein 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AP001178
    Consensus CDS
    CCDS42405.1
    UniProtKB/Swiss-Prot
    A0FDN7
    Related
    ENSP00000441726.2, ENST00000540035.5
    Conserved Domains (1) summary
    pfam01093
    Location:33462
    Clusterin
  2. NM_001318522.2NP_001305451.1  clusterin-like protein 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AP001178
    Consensus CDS
    CCDS42405.1
    UniProtKB/Swiss-Prot
    A0FDN7, Q15846
    Related
    ENSP00000464642.1, ENST00000579494.1
    Conserved Domains (1) summary
    pfam01093
    Location:33462
    Clusterin
  3. NM_001375492.2NP_001362421.1  clusterin-like protein 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AP001178
    Consensus CDS
    CCDS42405.1
    UniProtKB/Swiss-Prot
    A0FDN7
    Conserved Domains (1) summary
    pfam01093
    Location:33462
    Clusterin
  4. NM_001393344.1NP_001380273.1  clusterin-like protein 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AP001178
    Consensus CDS
    CCDS42405.1
    UniProtKB/Swiss-Prot
    A0FDN7
    Related
    ENSP00000510271.1, ENST00000692774.1
    Conserved Domains (1) summary
    pfam01093
    Location:33462
    Clusterin
  5. NM_001393345.1NP_001380274.1  clusterin-like protein 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AP001178
    Consensus CDS
    CCDS42405.1
    UniProtKB/Swiss-Prot
    A0FDN7
    Conserved Domains (1) summary
    pfam01093
    Location:33462
    Clusterin
  6. NM_001393346.1NP_001380275.1  clusterin-like protein 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AP001178
    Consensus CDS
    CCDS42405.1
    UniProtKB/Swiss-Prot
    A0FDN7
    Conserved Domains (1) summary
    pfam01093
    Location:33462
    Clusterin
  7. NM_001393347.1NP_001380276.1  clusterin-like protein 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AP001178
    Consensus CDS
    CCDS42405.1
    UniProtKB/Swiss-Prot
    A0FDN7
    Conserved Domains (1) summary
    pfam01093
    Location:33462
    Clusterin
  8. NM_001393348.1NP_001380277.1  clusterin-like protein 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AP001178
    Consensus CDS
    CCDS42405.1
    UniProtKB/Swiss-Prot
    A0FDN7
    Conserved Domains (1) summary
    pfam01093
    Location:33462
    Clusterin
  9. NM_014410.6NP_055225.1  clusterin-like protein 1 precursor

    See identical proteins and their annotated locations for NP_055225.1

    Status: VALIDATED

    Source sequence(s)
    AP001178
    Consensus CDS
    CCDS42405.1
    UniProtKB/Swiss-Prot
    A0FDN7, Q15846
    Related
    ENSP00000383449.2, ENST00000400606.6
    Conserved Domains (1) summary
    pfam01093
    Location:33462
    Clusterin
  10. NM_199167.2NP_954636.1  clusterin-like protein 1 precursor

    See identical proteins and their annotated locations for NP_954636.1

    Status: VALIDATED

    Source sequence(s)
    AP001178
    Consensus CDS
    CCDS42405.1
    UniProtKB/Swiss-Prot
    A0FDN7, Q15846
    Related
    ENSP00000341128.6, ENST00000338387.11
    Conserved Domains (1) summary
    pfam01093
    Location:33462
    Clusterin

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p14 Primary Assembly

    Range
    596988..650182
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011525651.3XP_011523953.1  clusterin-like protein 1 isoform X2

    See identical proteins and their annotated locations for XP_011523953.1

    Conserved Domains (3) summary
    smart00030
    Location:37248
    CLb; CLUSTERIN Beta chain
    smart00035
    Location:249471
    CLa; CLUSTERIN alpha chain
    pfam01093
    Location:44473
    Clusterin; Clusterin
  2. XM_011525648.4XP_011523950.2  clusterin-like protein 1 isoform X1

    Related
    ENSP00000463269.2, ENST00000581619.5

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060942.1 Alternate T2T-CHM13v2.0

    Range
    751354..804514
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)